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Riboflavin (Vitamin B-2)

Basic Information

Brand names:
Vitamin B-2 Tablets
Riboflavin(R)
Riobin-50(R)
Available from natural sources? Yes
Available from synthetic sources? Yes
Prescription required? No
Fat-soluble or water-soluble: Water-soluble

NATURAL SOURCES

Almonds
Brewer's yeast
Cheese
Chicken
Organ meats (beef, kidney)
Wheat germ

REASONS TO USE

  • Aids in release of energy from food.
  • Maintains healthy mucous membranes lining respiratory, digestive, circulatory and excretory tracts when used in conjunction with vitamin A.
  • Preserves integrity of nervous system, skin, eyes.
  • Promotes normal growth and development.
  • Aids in treating infections, stomach problems, burns, alcoholism, liver disease.

    UNPROVED SPECULATED BENEFITS

  • Cures various eye diseases.
  • Treats skin disorders.
  • Prevents cancer.
  • Increases body growth during normal developmental stages.
  • Helps overcome infertility.
  • Prevents stress.
  • Stimulates hair growth in bald men.
  • Improves vision.

    WHO NEEDS ADDITIONAL AMOUNTS?

  • Anyone with inadequate caloric or nutritional dietary intake or increased nutritional requirements.
  • Pregnant or breast-feeding women.
  • Those who abuse alcohol or other drugs.
  • People with a chronic wasting illness, excess stress for long periods or who have recently undergone surgery.
  • Athletes and workers who participate in vigorous physical activities.
  • Those with a portion of the gastrointestinal tract surgically removed.
  • People with recent severe burns or injuries.
  • Those who rely almost exclusively on processed foods for their daily diet.
  • Women taking oral contraceptives or estrogen.

    DEFICIENCY SYMPTOMS

  • Cracks and sores in corners of mouth
  • Inflammation of tongue and lips
  • Eyes overly sensitive to light and easily tired
  • Itching and scaling of skin around nose, mouth, scrotum, forehead, ears, scalp
  • Trembling
  • Dizziness
  • Insomnia
  • Slow learning
  • Itching, burning and reddening of eyes
  • Damage to cornea of eye

    UNPROVED SPECULATED SYMPTOMS

  • Mild anemia
  • Mild lethargy
  • Acne
  • Migraine headaches
  • Muscle cramps

    LAB TESTS TO DETECT DEFICIENCY

  • Serum riboflavin
  • Erythrocyte riboflavin
  • Glutathione reductase

    DOSAGE AND USAGE INFORMATION

    Age RDA
    0-6 months 0.4mg
    6-12 months 0.6mg
    1-3 years 0.8mg
    4-6 years 1.0mg
    7-10 years 1.4mg
    MALES
    11-14 years 1.6mg
    15-22 years 1.7mg
    23-50 years 1.6mg
    51+ years 1.4mg
    FEMALES
    11-22 years 1.3mg
    23+ years 1.2mg
    Pregnant +0.3mg
    Lactating +0.5mg
    What this mineral does:

  • Acts as component in two co-enzymes (flavin mononucleotide and flavin adenine dinucleotide) needed for normal tissue respiration.
  • Activates pyridoxine

    Miscellaneous information:

  • A balanced diet prevents deficiency without supplements.
  • Large doses may produce dark-yellow urine.
  • Processing food may decrease quantity of vitamin B-2.
  • Mixing with baking soda destroys riboflavin.

    Available as:

  • Tablets: Swallow whole with full glass of liquid. Don't chew or crush. Take with or immediately after food to decrease stomach irritation.
  • A constituent of many multivitamin/mineral preparations.

    WARNINGS AND PRECAUTIONS

    Don't take if you:

  • Are allergic to any B vitamin.
  • Have chronic kidney failure.

    Consult your doctor if you are:

  • Pregnant or planning a pregnancy.

    Over age 55:

  • Need for vitamin B-2 is greater.

    Pregnancy:

  • Don't take megadoses.

    Breast-feeding:

  • Don't take megadoses.

    Effect on lab tests:

  • Urinary catecholamine concentration may show false elevation.
  • Urobilongen determinations (Ehrlich's) may produce false-positive results.

    Storage:

  • Store in cool, dry place away from direct light, but don't freeze.
  • Store safely out of reach of children.
  • Don't store in bathroom medicine cabinet. Heat and moisture may change action of vitamin.

    Others:

  • Unlikely to cause toxic symptoms in healthy people with normal kidney function.

    OVERDOSE/TOXICITY

    Signs and symptoms:
    Dark urine, nausea, vomiting.

    What to do:

  • For symptoms of overdosage: Discontinue vitamin, and consult doctor. Also see ADVERSE REACTIONS OR SIDE EFFECTS section below.
  • For accidental overdosage (such as child taking entire bottle): Dial 911 (emergency), 0 for operator or your nearest Poison Control Center.

    ADVERSE REACTIONS OR SIDE EFFECTS

    Reaction or effect What to do
    Yellow urine, with large doses No action necessary.

    INTERACTION WITH MEDICINE, VITAMINS OR MINERALS

    Interacts with Combined effect
    Anti-depressants (tricyclic) Decreases B-2 effect.
    Phenothiazines Decreases B-2 effect.
    Probenecid Decreases B-2 effect.

    INTERACTION WITH OTHER SUBSTANCES

  • Tobacco decreases absorption. Smokers may require supplemental vitamin B-2.
  • Alcohol prevents uptake and absorption of vitamin B-2.

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