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Pantothenic Acid (Vitamin B-5)

Basic Information

Available from natural sources? Yes
Available from synthetic sources? Yes
Prescription required? Yes, for injectable forms
Fat-soluble or water-soluble: Water-soluble

NATURAL SOURCES

Blue cheese
Brewer's yeast
Corn
Eggs
Lentils
Liver
Lobster
Meats, all kinds
Peanuts
Peas
Soybeans
Sunflower seeds
Wheat germ
Whole grain products

REASONS TO USE

  • Promotes normal growth and development.
  • Aids in release of energy from foods.
  • Helps synthesis of numerous body materials.

    UNPROVED SPECULATED BENEFITS

  • Stimulates wound healing.
  • Alleviates stress.
  • Restores gray hair to normal hair color.
  • Prevents hair from turning gray.
  • Cures allergies.
  • Treats alcoholism, liver cirrhosis.
  • Treats constipation.
  • Treats fatigue.
  • Treats stomach ulcers.
  • Retards aging.

    WHO NEEDS ADDITIONAL AMOUNTS?

  • Anyone with inadequate caloric or nutritional dietary intake or increased nutritional requirements.
  • Older people (over 55 years).
  • Pregnant or breast-feeding women.
  • Those who abuse alcohol or other drugs.
  • People with a chronic wasting illness, excess stress for long periods or who have recently undergone surgery.
  • Athletes and workers who participate in vigorous physical activities.
  • People with a portion of the gastrointestinal tract surgically removed.
  • People with recent severe burns or injuries.

    DEFICIENCY SYMPTOMS

    None proved for pantothenic acid alone. However, lack of one B
    vitamin usually means lack of other B nutrients. Pantothenic
    acid is usually given with other B vitamins if there are
    symptoms of ANY vitamin-B deficiency, including excessive
    fatigue, sleep disturbances, loss of appetite, nausea.

    UNPROVED SPECULATED SYMPTOMS

  • Nerve damage
  • Breathing problems
  • Skin problems
  • Gray hair
  • Arthritis
  • Allergies
  • Birth defects
  • Mental fatigue
  • Headaches
  • Sleep disturbances
  • Muscle spasms, cramps

    LAB TESTS TO DETECT DEFICIENCY

    Methods are limited and expensive. Tests are used only for
    research at present. Methods are available to measure blood
    levels and levels in 24-hour urine collections.

    DOSAGE AND USAGE INFORMATION

    Age Estimated Safe Intake
    0-6 months 2mg/day
    6 months-3 years 3mg/day
    4-6 years 3-4mg/day
    7-9 years 4-5mg/day
    10+ years 4-7mg/day
    Pregnancy and lactation may increase the need by one-third.
    What this vitamin does:

  • Acts as co-enzyme in energy metabolism of carbohydrates, protein and fat.

    Available as:

  • Tablets: Swallow whole with full glass of liquid. Don't chew or crush. Take with meals or 1 to 1-1/2 hours after meals unless otherwise directed by your doctor.
  • A constituent of many multivitamin/mineral preparations.
  • Pantothenic acid is also sold as dexpanthenol (panthoderm), a lotion or cream applied to burns, cuts or abrasions. It relieves itching and soothes the wound.

    WARNINGS AND PRECAUTIONS

    Don't take if you:

  • Are allergic to pantothenic acid.
  • Are taking levodopa for Parkinson's disease.

    Consult your doctor if you have:

  • Hemophilia.

    Over age 55:

  • No problems expected.

    Pregnancy:

  • Don't exceed recommended dose.

    Breast-feeding:

  • Don't exceed recommended dose.

    Effect on lab tests:

  • None expected.

    Storage:

  • Store in cool, dry place away from direct light, but don't freeze.
  • Store safely out of reach of children.
  • Don't store in bathroom medicine cabinet. Heat and moisture may change action of vitamin.

    Others:

  • Avoid megadoses.
  • Don't exceed recommended doses if you take pantothenic acid without medical supervision.

    OVERDOSE/TOXICITY

    Signs and symptoms:
    Diarrhea and water retention with ingestion of
    megadoses--over 10 to 20 grams/day (10,000mg-20,000mg). This
    dose is not life-threatening.

    What to do:

  • For symptoms of overdosage: Discontinue vitamin, and consult doctor.
  • For accidental overdosage (such as child taking entire bottle): Dial 911 (emergency), 0 for operator or your nearest Poison Control Center.

    ADVERSE REACTIONS OR SIDE EFFECTS

    Reaction or effect What to do
    None expected with normal intake Call doctor if you suspect
    new symptoms are caused by
    taking pantothenic acid.

    INTERACTION WITH MEDICINE, VITAMINS OR MINERALS

    Interacts with Combined effect
    Levodopa Small amounts of pantothenic
    acid nullify levodopa's
    effect. Carbidopa-levodopa
    combination is not affected by
    this interaction.

    INTERACTION WITH OTHER SUBSTANCES

  • Tobacco decreases absorption. Smokers may require supplemental vitamin B-5.

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