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TRIMETHOPRIM

TRIMETHOPRIM

BRAND & GENERIC NAMES

Apo-Sulfatrim
Bactrim
Cotrim
Novotrimel
Proloprim
Protrin
Rovbac
Septra
SMZ-TMP
Syraprim
Trimpex

BASIC INFORMATION

  • Habit forming? No
  • Prescription needed? Yes
  • Available as generic? Yes
  • Drug class: Antimicrobial

    USES

  • Treatment for urinary-tract infections susceptible to trimethoprim.
  • Helps prevent recurrent urinary-tract infections if taken once a day.

    DOSAGE & USAGE INFORMATION

    How to take:
    Tablet -- Swallow with liquid or food to lessen stomach
    irritation.
    When to take:
    Space doses evenly in 24 hours to keep constant amount in urine.
    If you forget a dose:
    Take as soon as possible. Wait 5 to 6 hours before next dose.
    Then return to regular schedule.
    What drug does:
    Stops harmful bacterial germs from multiplying. Will not kill
    viruses.

    Time lapse before drug works:
    2 to 5 days.
    Don't take with:
    Any other medicines, even over-the-counter drugs such as cough
    and cold medicines, nose drops, diet pills, laxatives or
    caffeine, without consulting your doctor.
    OVERDOSE
    SYMPTOMS:
    Nausea, vomiting, diarrhea.
    WHAT TO DO:
    Overdose unlikely to threaten life. If child takes much larger
    amount than prescribed, call doctor, poison-control center or
    hospital emergency room for instructions.

    POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS

    SYMPTOMS WHAT TO DO

    Life-threatening:
    None expected.
    Common:
    Rash, itchy skin. Discontinue. Seek emergency
    treatment.
    Infrequent:

  • Diarrhea, nausea, Discontinue. Call vomiting, abdominal doctor right away. pain.
  • Headache. Continue. Call doctor when convenient. Rare:
  • Blue fingernails, Discontinue. Seek lips and skin; emergency treatment. difficult breathing.
  • Sore throat, fever, Discontinue. Call anemia, jaundice. doctor right away.

    WARNINGS & PRECAUTIONS

    Don't take if:

  • You are allergic to trimethoprim or any sulfa drug.
  • You are anemic due to folic acid deficiency.

    Before you start, consult your doctor:
    If you have had liver or kidney disease.
    Pregnancy:
    Studies inconclusive on harm to unborn child. Animal studies
    show fetal abnormalities. Decide with your doctor whether drug
    benefits justify risk to unborn child.
    Infants & children:
    Use under medical supervision only.
    Prolonged use:
    Anemia.
    Skin & sunlight:
    May cause rash or intensify sunburn in areas exposed to sun or
    sunlamp.

    Driving or hazardous activities:
    No age-related problems expected.
    Discontinuing:
    Don't discontinue without doctor's advice until you complete
    prescribed dose, even though symptoms diminish or disappear.
    Others:
    No age-related problems expected.

    POSSIBLE INTERACTION WITH OTHER DRUGS

    Diuretics, thiazide Unusual bleeding or
    (see Drugs Glossary) bruising.
    Flecainide Possible decreased blood-cell
    production in bone marrow.
    Sulfamethoxazole Beneficial increase of
    sulfamethoxazole effect.
    Tocainide Possible decreased blood-cell
    production in bone marrow.

    POSSIBLE INTERACTION WITH OTHER SUBSTANCES

    Marijuana: None expected.
    Tobacco: None expected.

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