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SULFONAMIDES

SULFONAMIDES

BRAND & GENERIC NAMES

Apo-Sulfamethoxazole Protrin
Apo-Sulfatrim Renoquid
Azo Gantanol Roubac
Bactrim Septra
Cetamide SK-Soxazole
Co-trimoxazole SMZ-TMP
Cotrim SULFACYTINE
Cotrim D.S. Sulfafurazole
Gantanol Sulfamethoprim
Gantrisin SULFAMETHOXAZOLE
Lipo-Gantrisin SULFAMETHOXAZOLE &
Methoxanol TRIMETHOPRIM
Novosoxazole SULFISOXAZOLE
Novotrimel Sulmeprim

BASIC INFORMATION

  • Habit forming? No
  • Prescription needed? Yes
  • Available as generic? Yes
  • Drug class: Sulfa (sulfonamide)

    USES

    Treatment for urinary tract infections responsive to this drug.

    DOSAGE & USAGE INFORMATION

    How to take:

  • Tablet--Swallow with liquid. Instructions to take on empty stomach mean 1 hour before or 2 hours after eating.
  • Liquid--Shake carefully before measuring. When to take: At the same times each day, evenly spaced. If you forget a dose: Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose). What drug does: Interferes with a nutrient (folic acid) necessary for growth and reproduction of bacteria. Will not attack viruses.

    Time lapse before drug works:
    2 to 5 days to affect infection.
    Don't take with:
    Any other medicines, even over-the-counter drugs such as cough
    and cold medicines, nose drops, diet pills, laxatives or
    caffeine, without consulting your doctor.
    OVERDOSE
    SYMPTOMS:
    Less urine, bloody urine, coma.
    WHAT TO DO:

  • Dial 0 (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately.
  • See EMERGENCY INFORMATION.

    POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS

    SYMPTOMS WHAT TO DO

    Life-threatening:
    None expected.
    Common:

  • Itchy skin, rash. Discontinue. Call doctor right away.
  • Headache, nausea, Continue. Call doctor vomiting, diarrhea, when convenient. appetite loss. Infrequent:
  • Red, peeling or Discontinue. Call blistering skin; doctor right away. sore throat; fever; swallowing difficulty; unusual bruising; aching joints or muscles; jaundice.
  • Dizziness. Continue. Call doctor when convenient. Rare: Painful urination; Discontinue. Call low back pain; doctor right away. numbness, tingling, burning feeling in feet and hands.

    WARNINGS & PRECAUTIONS

    Don't take if:
    You are allergic to any sulfa drug.

    Before you start, consult your doctor:

  • If you are allergic to carbonic anhydrase inhibitors, oral antidiabetics or thiazide or loop diuretics.
  • If you are allergic by nature.
  • If you have liver or kidney disease.
  • If you have porphyria.
  • If you have developed anemia from use of any drug. Pregnancy: Risk to unborn child outweighs drug benefits. Don't use. Infants & children: Don't give to infants younger than 1 month. Prolonged use:
  • May enlarge thyroid gland.
  • You may become more susceptible to infections caused by germs not responsive to this drug.
  • Request frequent blood counts, liver-and kidney-function studies. Skin & sunlight: May cause rash or intensify sunburn in areas exposed to sun or sunlamp.

    Driving or hazardous activities:
    Avoid if you feel dizzy. Otherwise, no problems expected.
    Discontinuing:
    Don't discontinue without doctor's advice until you complete
    prescribed dose, even though symptoms diminish or disappear.
    Others:

  • Drink 2 quarts of liquid each day to prevent adverse reactions.
  • If you require surgery, tell anesthetist you take sulfa. Pentothal anesthesia should not be used.

    POSSIBLE INTERACTION WITH OTHER DRUGS

    Aminobenzoate Possible decreased
    potassium sulfa effect.
    Anticoagulants (oral, Increased
    see Drugs Glossary) anticoagulant effect.
    Anticonvulsants Toxic effect
    (hydantoin, on brain.
    see Drugs Glossary)
    Aspirin Increased sulfa effect.
    Calcium supplements Decreased sulfa effect.
    (see Drugs Glossary)
    Isoniazid Possible anemia.
    Methenamine Possible kidney blockage.
    Methotrexate Increased methotrexate effect.
    Oxyphenbutazone Increased sulfa effect.
    Para-aminosalicylic Decreased
    acid (PAS) sulfa effect.
    Penicillins Decreased penicillin
    (see Drugs Glossary) effect.
    Phenylbutazone Increased sulfa effect.
    Probenecid Increased sulfa effect.
    Sulfinpyrazone Increased sulfa effect.
    Sulfonureas May increase
    (see Drugs Glossary) hypoglycemic action.
    Trimethoprim Increased sulfa effect.

    POSSIBLE INTERACTION WITH OTHER SUBSTANCES

    Marijuana: None expected.
    Tobacco: None expected.

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