PENTOXIFYLLINE |
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PENTOXIFYLLINE
BRAND & GENERIC NAMES
Trental
BASIC INFORMATION
Habit forming? No
Prescription needed? Yes
Available as generic? No
Drug class: Hemorrheologic agent (see Drugs Glossary)
USES
Reduces pain in legs caused by poor circulation.
DOSAGE & USAGE INFORMATION
How to take:
Extended-release tablets -- Swallow whole with water and food.
When to take:
At mealtimes. Taking with food decreases the likelihood of
irritating the stomach and cause nausea.
If you forget a dose:
Take as soon as you remember up to 3 hours late. If more than 3
hours, wait for next scheduled dose (don't double this dose).
What drug does:
Reduces "stickiness" of red blood cells and improves
flexibility of the red cells.
Improves blood flow through blood vessels.
Time lapse before drug works:
1 hour. Several weeks for full effect on circulation.
Don't take with:
Tobacco or medicines to treat hypertension.
Any other medicines, even over-the-counter drugs such as cough
and cold medicines, nose drops, diet pills, laxatives or
caffeine, without consulting your doctor.
OVERDOSE
SYMPTOMS:
Drowsiness, flushed face, fainting, nervousness, convulsions,
coma.
WHAT TO DO:
Dial 0 (operator) or 911 (emergency) for an ambulance or
medical help. Then give first aid immediately.
See EMERGENCY INFORMATION
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
SYMPTOMS WHAT TO DO
Life-threatening:
Chest pain, irregular Discontinue. Seek
heartbeat. emergency treatment.
Common:
None expected.
Infrequent:
Dizziness, headache, Discontinue. Call
nausea, vomiting. doctor right away.
low blood pressure,
nose bleed, swollen feet
and ankles, viral-like
syndrome, nasal
congestion, laryngitis,
rash, itchy skin,
blurred vision.
Insomnia,
nervousness, Continue. Call doctor
red eyes. when convenient.
Rare:
None expected.
WARNINGS & PRECAUTIONS
Don't take if:
You are allergic to pentoxifylline.
Before you start, consult your doctor:
If you are allergic to caffeine, theophylline, theobromine,
aminophyllin, dyphyllin, oxtriphylline, theobromine.
If you have angina.
Pregnancy:
Safety to unborn child unestablished. Avoid if possible.
Infants & children:
Don't give to infants or young children unless prescribed and
monitored by your physician.
Prolonged use:
No age-related problems expected.
Skin & sunlight:
No age-related problems expected.
Driving or hazardous activities:
Wait to see if drug causes drowsiness or dizziness. If none, no
problems expected.
Discontinuing:
No age-related problems expected.
Others:
Don't smoke.
POSSIBLE INTERACTION WITH OTHER DRUGS
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| Anticoagulants (oral, |
Possible decreased |
| see Drugs Glossary) |
effect of anticoagulant. |
| Anithypertensives |
Possible increased |
| (see Drugs Glossary) |
effect of hypertensive medication. |
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
| Marijuana: |
Decreased effect of pentoxifylline. |
| Tobacco: |
Decreased effect of pentoxifylline. |
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