DIURETICS, THIAZIDE |
|
DIURETICS, THIAZIDE
BRAND & GENERIC NAMES
Anhydron HydroDIURIL
Apo-Chlorthalidone Hydromox
Apo-Hydro Hygroton
Aquamox Metahydrin
Aquatag METHYCLOTHIAZIDE
Aquatensen METOLAZONE
BENDROFLUMETHIAZIDE Mictrin
BENZTHIAZIDE Naqua
CHLOROTHIAZIDE Natrimax
CHLORTHALIDONE Naturetin
CYCLOTHIAZIDE Neo-Codema
Diucardin Novohydrazide
Diuchlor H Novothalidone
Diulo Oretic
Diuril POLYTHIAZIDE
Duretic QUINETHAZONE
Enduron Renese
Esidrix Saluron
Exna Thalitone
Fluidil Thiuretic
Hydrex TRICHLORMETHIAZIDE
HYDROCHLOROTHIAZIDE Uridon
Hydrochlorothiazide Urozide
Intensol Zaroxolyn
HYDROFLUMETHIAZIDE
BASIC INFORMATION
Habit forming? No
Prescription needed? Yes
Available as generic? Yes
Drug class: Antihypertensive, diuretic (thiazide)
USES
Controls, but doesn't cure, high blood pressure.
Reduces fluid retention (edema).
DOSAGE & USAGE INFORMATION
How to take:
Tablet or liquid -- Swallow with liquid. If you can't swallow
whole, crumble tablet and take with liquid or food.
When to take:
At the same time each day.
If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2
hours, wait for next scheduled dose (don't double this dose).
What drug does:
Forces sodium and water excretion, reducing body fluid.
Relaxes muscle cells of small arteries.
Reduced body fluid and relaxed arteries lower blood pressure.
Time lapse before drug works:
4 to 6 hours. May require several weeks to lower blood pressure.
Don't take with:
Any other medicines, even over-the-counter drugs such as cough
and cold medicines, nose drops, diet pills, laxatives or
caffeine, without consulting your doctor.
OVERDOSE
SYMPTOMS:
Cramps, weakness, drowsiness, weak pulse, coma.
WHAT TO DO:
Dial 0 (operator) or 911 (emergency) for an ambulance or
medical help. Then give first aid immediately.
See EMERGENCY INFORMATION.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
SYMPTOMS WHAT TO DO
Life-threatening:
None expected.
Common:
None expected.
Infrequent:
Blurred vision, Discontinue. Call
severe abdominal doctor right away.
pain, nausea,
vomiting, irregular
heartbeat, weak pulse.
Dizziness, mood Continue. Call doctor
change, headache, when convenient.
weakness, tiredness,
weight changes.
Dry mouth, thirst. Continue. Tell doctor at next
visit.
Rare:
Rash or hives. Discontinue. Seek emergency
treatment.
Sore throat, Discontinue. Call
fever, jaundice. doctor right away.
WARNINGS & PRECAUTIONS
Don't take if:
You are allergic to any thiazide diuretic drug.
Before you start, consult your doctor:
If you are allergic to any sulfa drug.
If you have gout.
If you have liver, pancreas or kidney disorder.
Pregnancy:
Risk to unborn child outweighs drug benefits. Don't use.
Infants & children:
No age-related problems expected.
Prolonged use:
You may need medicine to treat high blood pressure for the rest
of your life.
Skin & sunlight:
May cause rash or intensify sunburn in areas exposed to sun or
sunlamp.
Driving or hazardous activities:
Don't drive or pilot aircraft until you learn how medicine
affects you. Don't work around dangerous machinery. Don't climb
ladders or work in high places. Danger increases if you
drink alcohol or take medicine affecting alertness and reflexes,
such as antihistamines, tranquilizers, sedatives, pain medicine,
narcotics and mind-altering drugs.
Discontinuing:
Don't discontinue without medical advice.
Others:
Hot weather and fever may cause dehydration and drop in blood
pressure. Dose may require temporary adjustment. Weigh daily and
report any unexpected weight decreases to your doctor.
May cause rise in uric acid, leading to gout.
May cause blood-sugar rise in diabetics.
POSSIBLE INTERACTION WITH OTHER DRUGS
|
|
|
| ACE inhibitors: |
Decreased blood |
| captopril, enalapril, |
pressure. |
| lisinopril (see |
| Drugs Glossary) |
| Allopurinol |
Decreased allopurinol effect. |
| Amiodarone |
Increased risk of heartbeat |
| |
irregularity due to low potassium. |
| Amphotericin B |
Increased potassium. |
| Antidepressants, |
Dangerous drop in |
| tricyclic (TCA, |
blood pressure. Avoid |
| see Drugs Glossary) |
combination unless under medical |
| |
supervision. |
| Antidiabetic agents |
Increased blood sugar. |
| (oral, see Drugs |
| Glossary) |
| Antihypertensives |
Increased hypertensive |
| (see Drugs Glossary) |
effect. |
| Barbiturates |
Increased |
| (see Drugs Glossary) |
diuretic effect. |
| Beta-adrenergic blockers |
Increased antihypertensive |
| (see Drugs Glossary) |
effect. Dosages of both drugs may |
| |
require adjustments. |
| Calcium supplements |
Increased calcium in |
| (see Drugs Glossary) |
blood. |
| Cholestyramine |
Decreased diuretic effect. |
| Colestipol |
Decreased diuretic effect. |
| Cortisone drugs |
Excessive potassium loss that |
| |
causes dangerous heart rhythms. |
| Digitalis |
Excessive potassium |
| preparations |
loss that causes dangerous |
| (see Drugs Glossary) |
heart rhythms. |
| Diuretics (thiazide, |
Increased effect of |
| see Drugs Glossary) |
other thiazide diuretics. |
| Indapamide |
Increased diuretic effect. |
| Indomethacin |
Decreased diuretic effect. |
| Labetolol |
Increased antihypertensive effects. |
| Lithium |
Increased effect of lithium. |
| MAO inhibitors |
Increased |
| (see Drugs Glossary) |
diuretic effect. |
| Nitrates |
Excessive blood-pressure drop. |
| Opiates Dizziness or weakness when standing |
|
| |
up after sitting or lying down. |
| Oxprenolol |
Increased antihypertensive effect. |
| |
Dosages of both drugs may require |
| |
adjustments. |
| Potassium supplements |
Decreased potassium |
| (see Drugs Glossary) |
effect. |
| Probenecid |
Decreased probenecid effect. |
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
| Marijuana: |
May increase blood pressure. |
| Tobacco: |
None expected. |
| ‡ |
|
|
|
|
Dserun mollit anim id est laborum. Lorem ipsum and sunt in culpa qui officias deserunt mollit. Excepteur plus sint occaecat the best cupidatat nonr proident, sunt in culpa qui officia deserunt mollit anim id est laborum. September 24, 2004
