BENZODIAZEPINES |
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BENZODIAZEPINES
BRAND & GENERIC NAMES
ALPRAZOLAM Novolorazem
Alzapam Novopoxide
Apo-Chlordiazepoxide Novoxapam
Apo-Diazepam OXAZEPAM
Apo-Flurazepam Ox-Pam
Apo-Lorazepam Paxipam
Apo-Oxazepam PRAZEPAM
Ativan Q-Pam
Centrax Razepam
CHLORDIAZEPOXIDE Reposans
CLONAZEPAM Restoril
CLORAZEPATE Rival
Dalmane Rivotril
DIAZEPAM Serax
D-Tran Sereen
Durapam Serenack
E-Pam SK-Lygen
FLURAZEPAM Solium
HALAZEPAM Som-Pam
Halcion Somnol
Klonopin Stress-Pam
Libritabs Temaz
Librium TEMAZEPAM
Lipoxide Tranxene
Loraz Tranxene T-Tab
LORAZEPAM Tranxene-SD
Medilium TRIAZOLAM
Meval Valium
MIDAZOLAM Valrelease
Neo-Calme Vivol
Novoclopate Xanax
Novodipam Zapex
Novoflupam
BASIC INFORMATION
Habit forming? Yes
Prescription needed? Yes
Available as generic? Yes
Drug class: Tranquilizer (benzodiazepine)
USES
Treatment for nervousness or tension.
Treatment for muscle spasm.
Treatment for convulsive disorders.
DOSAGE & USAGE INFORMATION
How to take:
Tablet, extended-release capsule or liquid -- Swallow with liquid.
If you can't swallow whole, crumble tablet or open capsule and
take with liquid or food.
When to take:
At the same time each day, according to instructions on
prescription label.
If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2
hours, wait for next scheduled dose (don't double this dose).
What drug does:
Affects limbic system of brain -- part that controls emotions.
Time lapse before drug works:
2 hours. May take 6 weeks for full benefit.
Don't take with:
Any other medicines, even over-the-counter drugs such as cough
and cold medicines, nose drops, diet pills, laxatives or
caffeine, without consulting your doctor.
OVERDOSE
SYMPTOMS:
Drowsiness, weakness, tremor, stupor, coma.
WHAT TO DO:
Dial 0 (operator) or 911 (emergency) for an ambulance or
medical help. Then give first aid immediately.
If the child is unconscious and not breathing, give mouth-to-
mouth breathing. If there is no heartbeat, use cardiac massage
and mouth-to-mouth breathing (CPR). Don't try to make the child
vomit. If you can't get help quickly, take the child to nearest
emergency facility.
See EMERGENCY INFORMATION.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
SYMPTOMS WHAT TO DO
Life-threatening:
None expected.
Common:
Clumsiness, Continue. Call doctor
drowsiness, dizziness. when convenient.
Infrequent:
Hallucinations, Discontinue. Call
confusion, doctor right away.
depression, irritability,
rash, itch, vision changes.
Constipation or Continue. Call doctor
diarrhea, nausea, when convenient.
vomiting, difficult
urination, vivid dreams.
Rare:
Slow heartbeat, Discontinue. Seek
breathing difficulty. emergency treatment.
Mouth, throat ulcers; Discontinue. Call
jaundice. doctor right away.
Decreased libido. Continue. Call doctor when
convenient.
WARNINGS & PRECAUTIONS
Don't take if:
You are allergic to any benzodiazepine.
You have myasthenia gravis.
You are active or recovering alcoholic.
Patient is younger than 6 months.
Before you start, consult your doctor:
If you have liver, kidney or lung disease.
If you have diabetes, epilepsy or porphyria.
Pregnancy:
Risk to unborn child outweighs drug benefits. Don't use.
Infants & children:
Use only under medical supervision for children older than 6
months.
Prolonged use:
May impair liver function.
Skin & sunlight:
No age-related problems expected.
Driving or hazardous activities:
Don't drive or pilot aircraft until you learn how medicine
affects you. Don't work around dangerous machinery. Don't climb
ladders or work in high places. Danger increases if you drink
alcohol or take medicine affecting alertness and reflexes.
Discontinuing:
Don't discontinue without consulting doctor. Dose may require
gradual reduction if you have taken drug for a long time. Doses
of other drugs may also require adjustment.
Others:
Hot weather, heavy exercise and profuse sweat may reduce
excretion and cause overdose.
Blood sugar may rise in diabetics, requiring insulin
adjustment.
POSSIBLE INTERACTION WITH OTHER DRUGS
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| Anticonvulsants |
Change in seizure |
| (see Drugs Glossary) |
frequency or severity. |
| Antidepressants |
Increased sedative |
| (see Drugs Glossary) |
effect of both drugs. |
| Antihistamines |
Increased sedative |
| (see Drugs Glossary) |
effect of both drugs. |
| Antihypertensives |
Excessively low blood |
| (see Drugs Glossary) |
pressure. |
| Contraceptives (oral, |
Increased benzodiazepine effect. |
| see Drugs Glossary) |
| Disulfiram |
Increased benzodiazepine effect. |
| Dronabinol |
Increased effects of both drugs. |
| |
Avoid. |
| Erythromycin |
Increased benzodiazepine effect. |
| Ketoconazole |
Increased benzodiazepine effect. |
| Levodopa |
Possible decreased levodopa effect. |
| MAO inhibitors |
Convulsions, deep |
| (see Drugs Glossary) |
sedation, rage. |
| Molindone |
Increased tranquilizer effect. |
| Narcotics |
Increased sedative effect of both |
| |
drugs. |
| Probenecid |
Increased benzodiazepine effect. |
| Sedatives |
Increased sedative |
| (see Drugs Glossary) |
effect of both drugs. |
| Sleep inducers |
Increased sedative |
| (see Drugs Glossary) |
effect of both drugs. |
| Tranquilizers |
Increased sedative |
| (see Drugs Glossary) |
effect of both drugs. |
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
| Marijuana: |
Heavy sedation. Avoid. |
| Tobacco: |
Decreased benzodiazepine effect. |
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