BARBITURATES |
|
BARBITURATES
BRAND & GENERIC NAMES
Alurate MEPHOBARBITAL
AMOBARBITAL METHARBITAL
Amytal Nembutal
APROBARBITAL Neo-Barb
Barbased Novopentobarb
Barbita Novosecobarb
BUTABARBITAL PENTOBARBITAL
Butalan PHENOBARBITAL
Buticaps Sarisol No. 2
Butisol SECOBARBITAL
Day-Barb SECOBARBITAL & AMOBARBITAL
Gardenal Seconal
Gemonil Solfoton
Lotusate TALBUTAL
Luminal Tuinal
Mebaral
BASIC INFORMATION
Habit forming? Yes
Prescription needed? Yes
Available as generic? Yes
Drug class: Sedative, hypnotic
(barbiturate), anticonvulsant
USES
Relieves insomnia (higher bedtime dose).
Prevents convulsions or seizures, such as epilepsy.
DOSAGE & USAGE INFORMATION
How to take:
Tablet, liquid or capsule -- Swallow with liquid or food to lessen
stomach irritation. If you can't swallow whole, crumble tablet
or open capsule and take with liquid or food.
When to take:
At the same times each day.
If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2
hours, wait for next scheduled dose (don't double this dose).
What drug does:
May partially block nerve impulses at nerve-cell connections.
Time lapse before drug works:
60 minutes.
Don't take with:
Any other medicines, even over-the-counter drugs such as cough
and cold medicines, nose drops, diet pills, laxatives or
caffeine, without consulting your doctor.
OVERDOSE
SYMPTOMS:
Deep sleep, weak pulse, coma.
WHAT TO DO:
Dial 0 (operator) or 911 (emergency) for an ambulance or
medical help. Then give first aid immediately.
See EMERGENCY INFORMATION.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
SYMPTOMS WHAT TO DO
Life-threatening:
Hives, rash, intense Seek emergency
itching, faintness treatment immediately.
soon after a dose
(anaphylaxis).
Common:
Dizziness, drowsiness, Continue. Call doctor
"hangover" effect. when convenient.
Infrequent:
Rash or hives, face Discontinue. Call
or lip swelling, doctor right away.
swollen eyelids,
sore throat, fever.
Depression, Continue. Call doctor
confusion, slurred when convenient.
speech, diarrhea,
nausea, vomiting,
joint or muscle pain.
Rare:
Agitation, slow Discontinue. Call
heartbeat, difficult doctor right away.
breathing, jaundice.
Unexplained bleeding Continue. Call doctor
or bruising. when convenient.
WARNINGS & PRECAUTIONS
Don't take if:
You are allergic to any barbiturate.
You have porphyria.
Before you start, consult your doctor:
If you have epilepsy.
If you have kidney or liver damage.
If you have asthma.
If you have anemia.
If you have chronic pain.
If you will have surgery within 2 months, including dental
surgery, requiring general or spinal anesthesia.
Pregnancy:
Risk to unborn child outweighs drug benefits. Don't use.
Infants & children:
Use only under doctor's supervision.
Prolonged use:
May cause addiction, anemia, chronic intoxication.
May lower body temperature, making exposure to cold
temperatures hazardous.
Skin & sunlight:
May cause rash or intensify sunburn in areas exposed to sun or
sunlamp.
Driving or hazardous activities:
Don't drive or pilot aircraft until you learn how medicine
affects you. Don't work around dangerous machinery. Don't climb
ladders or work in high places. Danger increases if you drink
alcohol or take medicine affecting alertness and reflexes.
Discontinuing:
May be unnecessary to finish medicine. Follow doctor's
instructions. If you develop withdrawal symptoms of
hallucinations, agitation or sleeplessness after discontinuing,
call doctor right away.
Others:
Great potential for abuse.
POSSIBLE INTERACTION WITH OTHER DRUGS
|
|
|
| Anticoagulants (oral, |
Decreased |
| see Drugs Glossary) |
anticoagulant effect. |
| Anticonvulsants |
Changed seizure |
| (see Drugs Glossary) |
patterns. |
| Antidepressants, |
Decreased |
| tricyclics (TCA, |
antidepressant effect. |
| see Drugs Glossary) |
Possible dangerous oversedation. |
| Antidiabetics (oral, |
Increased |
| see Drugs Glossary) |
barbiturate effect. |
| Antihistamines |
Dangerous sedation. |
| (see Drugs Glossary) |
Avoid. |
| Aspirin |
Decreased aspirin effect. |
| Beta-adrenergic |
Decreased effect |
| blockers (see |
of beta-adrenergic |
| Drugs Glossary) |
blocker. |
| Contraceptives (oral, |
Decreased |
| see Drugs Glossary) |
contraceptive effect. |
| Cortisone drugs |
Decreased cortisone |
| (see Drugs Glossary) |
effect. |
| Cyclosporine |
Decreased effect of cyclosporine. |
| Digitoxin |
Decreased digitoxin effect. |
| Disulfiram |
Possible increased barbiturate |
| |
effect. |
| Doxycycline |
Decreased doxycycline effect. |
| Dronabinol |
Increased effects of both drugs. |
| |
Avoid. |
| Estrogens |
Decreased estrogen |
| (see Drugs Glossary) |
effect. |
| Griseofulvin |
Decreased griseofulvin effect. |
| Indapamide |
Increased indapamide effect. |
| Leucovorin |
May counteract anticonvulsant |
| (large doses) |
effect of barbiturate |
| anticonvulsants. |
| Loxapine |
Decreased anticonvulsant effect of |
| |
all barbiturate anticonvulsants. |
| MAO inhibitors |
Increased |
| (see Drugs Glossary) |
barbiturate effect. |
| Metronidazole |
Possible decreased metronidazole |
| |
effect. |
| Mind-altering drugs |
Dangerous sedation. |
| (see Drugs Glossary) |
Avoid. |
| Molindone |
Increased sedative effect. |
| Narcotics |
Dangerous sedation. |
| (see Drugs Glossary) |
Avoid. |
| Non-steroidal |
Decreased |
| anti-inflammatory |
anti-inflammatory |
| drugs (NSAIDs, |
effect. |
| see Drugs Glossary) |
| Pain relievers |
Dangerous sedation. |
| (see Drugs Glossary) |
Avoid. |
| Quinidine |
Decreased quinidine effect. |
| Rifampin |
Possible decreased barbiturate |
| |
effect. |
| Sedatives |
Dangerous sedation. |
| (see Drugs Glossary) |
Avoid. |
| Sleep inducers |
Dangerous sedation. |
| (see Drugs Glossary) |
Avoid. |
| Tranquilizers |
Dangerous sedation. |
| (see Drugs Glossary) |
Avoid. |
| Valproic acid |
Increased barbiturate effect. |
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
|
|
|
| Tobacco: |
None expected. |
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