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ACYCLOVIR (ORAL & TOPICAL)

ACYCLOVIR (ORAL & TOPICAL)

BRAND AND GENERIC NAMES

Zovirax
Zovirax Ointment

BASIC INFORMATION

  • Habit forming? No
  • Prescription needed? Yes
  • Available as generic? No
  • Drug class: Antiviral

    USES

  • Treatment of severe herpes infections of genitals occurring for first time in special cases.
  • Treatment of severe herpes infections on mucous membrane of mouth and lips in special cases.
  • Used (although not yet approved by FDA) for shingles (herpes zoster) and chickenpox (varicella) in special cases.

    DOSAGE & USAGE INFORMATION

    How to take:

  • Capsule--Swallow with liquid.
  • Ointment--Apply to skin and mucous membranes every 3 hours (6 times a day) for 7 days. Use rubber glove when applying. Apply 1/2-inch strip to each sore or blister. Wash before using. When to use: As directed on label. If you forget a dose: Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose). What drug does: Inhibits reproduction of virus in cells without killing normal cells.

    Time lapse before drug works:
    2 hours.
    Don't take with:
    Any other medicines, even over-the-counter drugs such as cough
    and cold medicines, nose drops, diet pills, laxatives or
    caffeine, without consulting your doctor.
    OVERDOSE
    SYMPTOMS:
    Hallucinations, seizures, kidney shutdown.
    WHAT TO DO:

  • Dial 0 (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately.
  • See EMERGENCY INFORMATION.

    POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS

    SYMPTOMS WHAT TO DO

    Life-threatening:
    None expected.
    Common:
    Rash, hives, itch, Continue. Call doctor
    mild pain, burning or when convenient.
    stinging of skin,
    lightheadedness,
    headache.
    Infrequent:
    Confusion, Discontinue. Call
    hallucinations, doctor right away.
    trembling.
    Rare:
    Abdominal pain, Discontinue. Call
    decreased appetite, doctor right away.
    nausea, vomiting,
    breathing difficulty,
    blood in urine,
    decreased urine volume.

    WARNINGS & PRECAUTIONS

    Don't take if:
    You are allergic to acyclovir.

    Before you start, consult your doctor:

  • If pregnant or plan pregnancy.
  • If breast-feeding.
  • If you have kidney disease.
  • If you have any nerve disorder. Pregnancy: Risk to unborn child outweighs drug benefits. Don't use. Infants & children: Use only under special medical supervision by experienced clinician. Prolonged use: Don't use longer than prescribed time. Skin & sunlight: No age-related problems expected.

    Driving or hazardous activities:
    No age-related problems expected.
    Discontinuing:
    May be unnecessary to finish medicine. Follow doctor's
    instructions.
    Others:

  • Females: Get Pap smear every 6 months because women with herpes infections are more likely to develop cancer of cervix. Avoid sexual activity until all blisters or sores heal. Don't get medicine in eyes.
  • Protect medicine from freezing.
  • Check with doctor if no improvement in 1 week.

    POSSIBLE INTERACTION WITH OTHER DRUGS

    Interferon Neurological abnormalities. Avoid.
    Methotrexate Neurological abnormalities. Avoid.
    Other medications Possible increased
    that can cause kidney toxicity.
    toxic effects on kidneys:
    Amikacin
    Amphotericin B
    Capreomycin
    Colistimethate
    Colistin
    Gentamycin
    Kanamycin
    Neomycin
    Netilmicin
    Polymixin B
    Probenecid
    Streptomycin
    Tobramycin
    Vancomycin

    POSSIBLE INTERACTION WITH OTHER SUBSTANCES

    Tobacco: None expected.

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