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DIC (Disseminated Intravascular Coagulation; Defibrinogenation Syndrome; Coagulopathy)

DESCRIPTION

Disseminated intravascular coagulation is a serious disruption of blood-clotting mechanisms, resulting in hemorrhaging or internal bleeding. This disorder is a complication of an underlying disorder. Blood vessels and blood in all parts of the body are involved.
Appropriate health care includes:
  • Hospitalization.
  • Physician's monitoring of general condition and medications.
  • Surgery to correct the underlying disorder (sometimes).
  • Self-care after diagnosis.

    SIGNS & SYMPTOMS

  • Bleeding and hemorrhaging from any or several body parts. Bleeding may be heavy. Common signs of bleeding include: -- Bloody vomit or red or black stools. -- Vaginal bleeding. -- Red or cloudy urine. -- Unexplained bruising.
  • Severe abdominal or back pain caused by bleeding into body organs.
  • Convulsions (rare).
  • Coma (rare).

    CAUSES
    Depletion of blood-clotting components, causing widespread bleeding. This condition can be the result of:

  • Pregnancy abnormalities, such as placenta previa, abruptio placenta, or toxemia.
  • Widespread or major infection.
  • Widespread cancer.
  • Some kinds of surgery.
  • Widespread tissue destruction, as with extensive burns.
  • Poisonous snakebite.
  • Transfusion of mismatched blood.

    RISK FACTORS

  • Poor nutrition.
  • Illness that has lowered resistance.

    PREVENTING COMPLICATIONS OR RECURRENCE

    Obtain prompt medical treatment for the underlying causes.

    BASIC INFORMATION

    MEDICAL TESTS

  • Your own observation of symptoms.
  • Medical history and physical exam by a doctor.
  • Laboratory blood tests, especially of the blood-clotting mechanism.

    POSSIBLE COMPLICATIONS

  • Kidney failure.
  • Brain damage, with seizures or coma.
  • Shock.
  • Death.

    PROBABLE OUTCOME
    Depends on the severity. If the underlying cause of the child's DIC is treated promptly, full recovery is likely.

    TREATMENT

    HOME CARE

  • Children with this condition are often desperately ill and require intensive hospital care. Family members can help by maintaining a positive, hopeful attitude.
  • During your child's recovery, don't scrub or take scabs off sores. This may trigger new bleeding.

    MEDICATION
    Your doctor may prescribe:

  • Blood transfusions or blood-component infusions.
  • Heparin (an anticoagulant administered by injection).
  • See Medications section for information regarding medicines your doctor may prescribe.

    ACTIVITY
    Your child should rest in bed until your doctor approves a return to normal activity. The child may read or watch TV.

    DIET & FLUIDS
    No special diet.

    OK TO GO TO SCHOOL?

    When signs of infection have decreased, appetite returns, and alertness, strength, and feeling of well-being will allow.

    CALL YOUR DOCTOR IF

  • Your child has symptoms of DIC.
  • Any bleeding recurs or the child's abdomen swells rapidly during treatment. ‡
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