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DIABETES INSIPIDUS

DESCRIPTION

Diabetes insipidus is a temporary disorder of the hormone system, centered in the pituitary gland. The pituitary gland and the endocrine system are involved.
Appropriate health care includes:
  • Physician's monitoring of general condition and medications.
  • Self-care after diagnosis.
  • Surgery if a tumor or aneurysm is present.
  • If brain surgery is necessary, see craniotomy (in Glossary) for an explanation of surgery and postoperative care.

    SIGNS & SYMPTOMS

  • Excessive thirst that is difficult to satisfy.
  • Passage of large amounts (up to 15 quarts a day) of diluted, colorless urine.
  • Dry hands.
  • Constipation.

    CAUSES
    Deficiency of an anti-diuretic hormone (ADH) normally secreted by the pituitary gland. The deficiency may result from the following:

  • Head injury, with damage to the pituitary gland.
  • Tumor of the pituitary gland.
  • Another type of brain tumor that applies pressure to the pituitary gland.
  • Infection in the brain, such as encephalitis or meningitis.
  • Bleeding inside the skull.
  • Aneurysm.
  • Kidney disease.

    RISK FACTORS

  • Preceding illness or injury in the brain.
  • Atherosclerosis (hardening of the arteries).
  • Family history of diabetes insipidus.

    PREVENTING COMPLICATIONS OR RECURRENCE

    No specific preventive measures.

    BASIC INFORMATION

    MEDICAL TESTS

  • Your own observation of symptoms.
  • Medical history and physical exam by a doctor.
  • Laboratory studies, such as water-deprivation tests to determine levels of ADH.

    POSSIBLE COMPLICATIONS

    Electrolyte imbalance, especially increased sodium or potassium deficiency. Either of these can cause heartbeat irregularity, fatigue, and congestive heart failure.

    PROBABLE OUTCOME

  • If the child's disorder is caused by a tumor or aneurysm, it can be cured by surgery.
  • If the disorder is caused by a head injury, spontaneous recovery is likely within a year.
  • If the disorder is caused by a preceding brain infection, symptoms may persist indefinitely.

    TREATMENT

    HOME CARE

    Follow physician's advice.

    MEDICATION

  • Your doctor may prescribe synthetic ADH in nose drops, powder or injection form.
  • See Medications section for information regarding medicines your doctor may prescribe.

    ACTIVITY
    No restrictions.

    DIET & FLUIDS
    No special diet. Your child should drink as much water as needed.

    OK TO GO TO SCHOOL?

    When appetite has returned and alertness, strength, and feeling of well-being will allow.

    CALL YOUR DOCTOR IF

  • Your child has symptoms of diabetes insipidus.
  • Symptoms don't improve, despite treatment.
  • New, unexplained symptoms develop. Drugs used in treatment may produce side effects. ‡
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