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Brand & Generic Names

Accurbron Slo-bid
Aerolate Slo-bid Gyrocaps
Aerolate III Slophyllin
Aerolate Jr. Slo-Phyllin
Aerolate Sr. Slo-Phyllin Gyrocaps
Aerophyllin Solu-Phyllin
Aminophyllin Somophyllin
AMINOPHYLLINE Somophyllin-12
Apo-Oxtriphylline Somophyllin-CRT
Aquaphyllin Somophyllin-DF
Asbron Somophyllin-T
Asmalix Sustaire
Bronkodyl Synophylate
Choledyl T.E.H.
Choledyl Delayed-Release T.E.P.
Choledyl SA Theo-24
Constant-T Theo-250
Corophyllin Theobid Duracaps
Dilor Theobid Jr. Duracaps
Dilor-400 Theochron
Duraphyl Theoclear-80
Dyflex Theoclear L.A. 130 Cenules
Dyflex 400 Theoclear L.A. 260 Cenules
Elixicon Theo-Dur
Elixomin Theo-Dur Sprinkle
Elixophyllin Theolair
Elixophyllin SR Theolair-SR
Lanophyllin Theomar
Lixolin Theon
Lufyllin-400 Theophylline SR
Neothylline Theo-Sav
Novotriphyl Theospan SR
Palaron Theostat
Phyllocontin Theostat 80
Phyllocontin-350 Theo-Time
PMS Theophylline Theox
Primatene, P Formula Theovent Long-acting
Protophylline Thylline
Pulmophylline T-Phyl
Quibron-T Truphylline
Quibron-T Dividose Truxophyllin
Quibron-T/SR Dividose Uniphyl

Basic Information

  • Habit forming? No
  • Prescription needed? U.S.: High Strength--Yes Low Strength--No Canada: No
  • Available as generic? Yes
  • Drug class: Bronchodilator (xanthine)


    Treatment for bronchial asthma symptoms.

Dosage & Usage Information

How to take:
Tablet or capsule--Swallow with liquid.
Extended-release tablets or capsules--Swallow each dose whole. If you take regular tablets, you may chew or crush them.
Suppositories--Remove wrapper and moisten suppository with water. Gently insert larger end into rectum. Push well into rectum with finger.
Syrup--Take as directed on bottle.
Enema--Use as directed on label.

When to take:
Most effective taken on empty stomach 1 hour before or 2 hours after eating. However, may take with food to lessen stomach upset.

If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Relaxes and expands bronchial tubes.

Time lapse before drug works:
15 to 30 minutes.

Don't take with:
Any other medicine without consulting your doctor or pharmacist.


Restlessness, irritability, confusion, black or tarry stool, breathing difficulty, pounding and irregular heartbeat, vomiting blood, delirium, convulsions, rapid pulse, coma.


  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • See EMERGENCY information.

Possible Adverse Reactions or Side Effects


    In case of overdose, see previous entry.


    Headache, irritability, nervousness, nausea, restlessness, insomnia, vomiting, stomach pain.


  • Rash or hives, flushed face, diarrhea, appetite loss, rapid breathing, irregular heartbeat.
  • Dizziness or lightheadedness.


    Frequent urination.

Warnings & Precautions

Don't take if:

  • You are allergic to any bronchodilator.
  • You have an active peptic ulcer.

Before you start, consult your doctor:

  • If you have had impaired kidney or liver function.
  • If you have gastritis.
  • If you have a peptic ulcer.
  • If you have high blood pressure or heart disease.
  • If you take medication for gout.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons.

Risk to unborn child outweighs drug benefits. Don't use.

Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine. Consult doctor for advice on maintaining milk supply.

Infants & children:
Use only under medical supervision.

Prolonged use:
Stomach irritation.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
Avoid if lightheaded or dizzy. Otherwise, no problems expected.

May be unnecessary to finish medicine. Follow doctor's instructions.

No problems expected.

Possible Interaction with Other Drugs

------------------------- -----------------------
Allopurinol Increased allopurinol effect.
Aminoglutethimide Possible decreased bronchodilator
Beta-agonists* Increased effect of both drugs.
Beta-adrenergic Decreased bronchodilator effect.
Cimetidine Increased bronchodilator effect.
Ciprofloxin Increased xanthine bronchodilator in
blood. Dosage adjustments necessary.
Clarithromycin Increased concentration of theophylline.
Clindamycin May increase bronchodilator effect.
Corticosteroids* Possible increased bronchodilator
Erythromycin Increased bronchodilator effect.
Finasteride Decreased theophylline effect.
Furosemide Increased furosemide effect.
Lincomycins* May increase bronchodilator effect.
Lithium Decreased lithium effect.
Moricizine Decreased bronchodilator effect.
Nicotine chewing gum Possible increased bronchodilator
Norfloxacin Increased xanthine bronchodilator in
blood. Dosage adjustments necessary.
Phenobarbital Decreased bronchodilator effect.
Phenytoin Decreased bronchodilator effect.
Probenecid Increased effect of dyphylline.
Ranitidine Possible increased bronchodilator effect
and toxicity.
Rauwolfia alkaloids* Rapid heartbeat.
Rifampin Decreased bronchodilator effect.
Sulfinpyrazine Increased effect of dyphylline.
Sympathomimetics* Possible increased bronchodilator
Tacrine Increased bronchodilator effect.
Ticlopidine Increased theophylline effect.
Troleandomycin Increased bronchodilator effect.

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: None expected.
Caffeine drinks. Nervousness and insomnia.
Cocaine: Excess stimulation. Avoid.
Foods: None expected.
Marijuana: Slightly increased antiasthmatic effect
of bronchodilator.
Decreased effect with chronic use.
Tobacco: Decreased bronchodilator effect.

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