APPETITE SUPPRESSANTS

Brand & Generic Names

Adipex-P	PHENDIMETRAZINE
Adipost	PHENMETRAZINE
Adphen	Phentercot
Anorex	PHENTERMINE
Anoxine-AM	Phenterxene
Appecon	Phentra
Bacarate	Phentride
BENZPHETAMINE	Phentrol
Bontril PDM	Phenzine
Bontril Slow Release	Plegine
Dapex-37.5	Ponderal
Didrex	Ponderal Pacaps
DIETHYLPROPION	Pondimin
Dital	Pondimin Extentabs
Dyrexan-OD	Prelu-2
Fastin	Preludin-Endurets
FENFLURAMINE	PT 105
Ionamin	Rexigen
M-Orexic	Rexigen Forte
Marlibar A	Sanorex
MAZINDOL	Slynn-LL
Mazanor	Span-RD
Melfiat-105 Unicelles	Statobex
Metra	T-Diet
Nobesine	Tega-Nil
Obalan	Tenuate
Obe-Del	Tenuate Dospan
Obe-Mar	Tepanil
Obe-Nix	Tepanil Ten-Tab
Obephen	Teramin
Obermine	Trimcaps
Obestin-30	Trimstat
Obeval	Trimtabs
Obezine	Uni Trim
Oby-Trim	Wehless
Panrexin M	Wehless Timecelles
Panrexin MTP	Weightrol
Panshape	Wescoid
Parmine	Wilpowr
Parzine	X-Trozine
Phendiet	X-Trozine LA
Phendimet	Zantryl

Basic Information

• Habit forming? Yes
• Prescription needed? Yes
• Available as generic? Yes
• Drug class: Appetite suppressant

Uses

Suppresses appetite.

Dosage & Usage Information

How to take:
Tablet or capsule--Swallow with liquid. You may chew or crush tablet.
Extended-release tablets or capsules-- Swallow each dose whole with liquid; do not crush.
Elixir--Swallow with liquid.

When to take:
Long-acting forms--10 to 14 hours before bedtime.
Short-acting forms--1 hour before meals. Last dose no later than 4 to 6 hours before bedtime.

If you forget a dose:
Long-acting form--Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).
Short-acting form--Wait for next scheduled dose. Don't double this dose.

What drug does:
Apparently stimulates brain's appetite-control center.

Time lapse before drug works:
Begins in 1 hour. Short-acting form lasts 4 hours. Long-acting form lasts 14 hours.

Don't take with:
Non-prescription drugs without consulting doctor.
Any other medicine without consulting your doctor or pharmacist.

Overdose

SYMPTOMS:
Irritability, overactivity, trembling, insomnia, mood changes, fever, rapid heartbeat, confusion, disorientation, hallucinations, convulsions, coma.

WHAT TO DO:

• Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
• See EMERGENCY Information.

Possible Adverse Reactions or Side Effects

Life-threatening:

In case of overdose, see Overdose section.

Common:

Irritability, nervousness, insomnia, false sense of well-being.

Infrequent:

• Irregular or pounding heartbeat, urgent or difficult urination.
• Blurred vision, unpleasant taste or dry mouth, constipation or diarrhea, nausea, vomiting, cramps, changes in sex drive, increased sweating, headache, nightmares, weakness.

Rare:

• Mood changes, rash or hives, breathing difficulty.
• Hair loss.

Warnings & Precautions

Don't take if:

• You are allergic to any sympathomimetic or phenylpropanolamine.
• You have glaucoma.
• You have taken MAO inhibitors within 2 weeks.
• You plan to become pregnant within medication period.
• You have a history of drug or alcohol abuse.
• You have irregular or rapid heartbeat.

Before you start, consult your doctor:

• If you have high blood pressure or heart disease.
• If you have an overactive thyroid, nervous tension or anxiety.
• If you have epilepsy.
• If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.
• If you take any other over-the-counter medicine.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons.

Pregnancy:
Safety not established. Avoid.

Breast-feeding:
Safety not established. Consult doctor.

Infants & children:
Don't give to children younger than 12.

Prolonged use:

• Loses effectiveness. Avoid.
• Talk to your doctor about the need for follow-up medical examinations or laboratory studies.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes, such as antihistamines, tranquilizers, sedatives, pain medicine, narcotics and mind-altering drugs.

Discontinuing:
Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment.

Others:
Don't increase dose.

Possible Interaction with Other Drugs

GENERIC NAME	COMBINED EFFECT
------------------------	-----------------------
Antihypertensives*	Decreased antihypertensive effect.
Appetite suppressants,	Dangerous
other*	overstimulation.
Caffeine	Increased stimulant effect.
Central nervous	Increased depressive effects of both
system (CNS)	drugs.
Central nervous	Increased stimulant effects of both
system (CNS)	drugs.
Furazolidine	Sudden severe increase in blood pressure.
Guanethidine	Decreased guanethidine effect.
Hydralazine	Decreased hydralazine effect.
MAO inhibitors*	Dangerous blood pressure rise.
Methyldopa	Decreased methyldopa effect.
Molindone	Decreased suppressant effect.
Phenothiazines*	Decreased appetite suppressant
	effect.
Rauwolfia alkaloids*	Decreased effect of rauwolfia
	alkaloids.
Sodium bicarbonate	Increased action of appetite
	suppressants.

Possible Interaction with Other Substances

INTERACTS WITH	COMBINED EFFECT
---------------	---------------
Beer, Chianti	Increased sedation.
> Caffeine drinks.	Excessive stimulation.
> Drinks containing	Blood-pressure rise.
Cocaine	Convulsions or excessive
	nervousness.
Foods containing	Blood-pressure rise.
Marijuana:	Frequent use--Irregular heartbeat.
Tobacco:	None expected.
=============================	===============================
POSSIBLE INTERACTION WITH OTH	ER SUBSTANCES
-----------------------------	-------------------------------
INTERACTS WITH	COMBINED EFFECT
---------------	---------------
Beer, Chianti	Increased sedation.
Caffeine drinks.	Excessive stimulation.
Drinks containing	Blood-pressure rise.
Cocaine:	Convulsions or excessive
	nervousness.
Foods containing	Blood-pressure rise.
Marijuana:	Frequent use--Irregular heartbeat.
Tobacco:	None expected.