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Brand & Generic Names

4 Way Cold Histabid Duracaps
12-Hour Cold Histadyl E.C.
Aclophen Histafed C
Actacin Histagesic Modified
Actagen-C Cough Histaject Modified
Actidil Histalet
Actifed Histalet-DM
Actifed 12-Hour Histalet Forte
Actifed A Histamic
Actifed DM Histatab Plus
Actifed Plus Histatan
Actifed w/Codeine Cough Histatuss Pediatric
Advanced Formula Dristan Hista-Vadrin
Alamine Histor-D
Alamine-C Liquid Histosal
Alersule Histussin C
Alka-Seltzer Plus Cold Hycomine
Alka-Seltzer Plus Maximum Hycomine Compound
Strength Sinus Allergy Hycomine-S Pediatric
Alka-Seltzer Plus Nighttime Hydramine
Cold Hydramine Cough
Allent Hydrate
Aller-Chlor Hydril
Alleract Hydroxacen
Allerdryl Hyrexin-50
Allerest Improved Sino-Tuss
Allerest 12 Hour Insomnal
Allerest 12 Hour Caplets Isoclor
Allerest Headache Strength Isoclor Timesules
Allerest Sinus Pain Formula Klerist
Allerfrin Kolephrin
Allerfrin w/Codeine Kolephrin/DM
Allergy Formula Sinutab Kolephrin NN Liquid
Allergy Relief Medicine Kophane
AllerMax Kophane Cough and Cold
Allerphed Formula
Allert Korigesic
Amaril D Kronofed-A
Amaril D Spantab Kronofed-A Jr.
Ambay Cough Lanatuss Expectorant
Ambenyl Cough LORATADINE
Ambophen Expectorant Marmine
Anamine Maximum Strength Dristan
Anamine HD Cold Multi-Symptom Caplets
Anamine TD Maximum Strength Tylenol
Anaplex Allergy Sinus Caplets
Anatuss Medatussin Plus
Anatuss w/Codeine Meda Syrup Forte
Apo-Dimenhydrinate Medi-Flu
Aprodrine Medi-Flu Caplets
A.R.M. Maximum Strength Midahist DH
Caplets Motion-Aid
Atrofed Myfed
Atrohist Sprinkle Myfedrine Plus
Bayaminicol Myhistine DH
Baydec DM Drops Myidil
Bayhistine DH Myminic
BC Cold Powder Myphetane DC Cough
Beldin Cough Myphetapp
Belix Naldecon
Ben-Allergin-50 Naldecon Pediatric
Bena-D Naldelate
Bena-D 50 Naldelate Pediatric Syrup
Benadryl Nalgest
Benadryl Allergy/Sinus Napril
Headache Caplets Nasahist
Benadryl Complete Allergy Nasahist B
Benadryl Decongestant Nauseatol
Benadryl Plus ND Clear T.D.
Benadryl Plus Nighttime ND-Gesic
Liquid ND Stat Revised
Benahist 10 Nervine Night-time Sleep-Aid
Benahist 50 New-Decongest
Ben-Allergen 50 New-Decongest Pediatric Syrup
Benaphen Nico-Vert
Benoject-10 Nidryl
Benoject-50 Nighttime Pamprin
Benylin Cold Nisaval
Benylin Cough Nolahist
Benylin Decongestant Nolamine
Benylin w/Codeine Noradryl
Benylin-DM Norafed
Biphetane DC Cough Noraminic
BQ Cold Nordryl
Brexin Nordryl Cough
Brexin-L.A. Norel Plus
Bromanate DC Cough Normatane
Bromatap Normatane DC
Bromatapp Novafed A
Brombay Novahistex
Bromfed Novahistex C
Bromfed-AT Novahistex DH
Bromfed-DM Novahistex DH Expectorant
Bromfed-PD Novahistex DM
Bromophen T.D. Novahistine DH
Bromphen Novahistine DH Expectorant
Bromphen DC Novahistine DH Liquid
Brompheril Novopheniram
Bronkotuss Expectorant Nyquil Liquicaps
Brotane DX Cough NyQuil Nighttime Colds
Bydramine Cough Medicine
Caldomine-DH Forte Nytime Cold Medicine Liquid
Caldomine-DH Pediatric Nytol Maximum Strength
Calm X Nytol w/DPH
Calmylin w/Codeine Omni-Tuss
Carbinoxamine Compound Optimine
Carbiset Oragest S.R.
Carbodec Oraminic II
Carbodec DM Drops Oraminic Spancaps
Carbodec TR Ornade
Cardec-S Ornade A.F.
Cenafed Plus Ornade Expectorant
Cerose-DM Ornade Spansules
Cheracol Plus Ornade-DM 10
Cheracol Sinus Ornade-DM 15
Chexit Ornade-DM 30
Children's Dramamine Orthoxicol Cough
Children's Nyquil Night- Panadyl
time Cold Medicine Par Decon
Children's Tylenol Cold PBZ
Chlo-Amine PBZ-SR
Chlor-100 PediaCare Allergy
Chlorafed PediaCare Children's Cold
Chlorafed H.S. Timecelles Relief Night Rest
Chlorafed Timecelles Cough-Cold Formula
Chlorate PediaCare Children's Cough-
Chlorgest-HD Cold Formula
Chlor-Niramine PediaCare Cold Formula
Chlorphed Pediacof Cough
Chlor-Pro Penntuss
Chlor-Pro 10 Periactin
Chlor-Rest Pertussin PM
Chlorspan-12 Pfeiffer's Allergy
Chlortab-4 Phanadex
Chlortab-8 Phenapapp Sinus Headache &
Chlor-Trimeton Congestion
Chlor-Trimeton Allergy Phenetron
Chlor-Trimeton Decongestant Phenetron Lanacaps
Chlor-Trimeton Repetabs PHENINDAMINE
Chlor-Trimeton Sinus Caplets PHENIRAMINE
Chlor-Tripolon Phentate T.D.
Chlor-Tripolon Decongestant Phentox Compound
Chlor-Tripolon Decongestant PHENYLTOLOXAMINE
Extra Strength PMS-Dimenhydrinate
Chlor-Tripolon Decongestant Poladex T.D.
Repetabs Polaramine
Citra Forte Polaramine Expectorant
Claritin Polaramine Repetabs
Clistin Poly-Histine-CS
CoActifed Poly-Histine D
CoActifed Expectorant Poly-Histine D Ped
Co-Apap Poly-Histine-DM
Codehist DH Prometh VC Plain
Codimal Prominicol Cough
Codimal-A Promist HD Liquid
Codimal DH Pseudo-Car DM
Codimal DM Pseudo-Chlor
Codimal L.A. Pseudodine C Cough
Codimal-LA Half Pseudo-gest Plus
Codimal PH P-V-Tussin
Colrex Compound Pyribenzamine
Coltab Children's Pyrilamine Maleate Tablets
Comhist Pyrroxate
Comhist LA Quelidrine Cough
Compoz Reactine
Comtrex A/S Reidamine
Comtrex Hot Flu Relief Remcol-C
Comtrex Multi-Symptom Remcol Cold
Cold Reliever Rentamine
Comtrex Multi-Symptom Resaid S.R.
Hot Flu Relief Resporal TR
Comtrex Nighttime Rhinolar-EX
Condrin LA Rhinolar-EX 12
Conex D.A. Rhinosyn-DM
Conex Plus Rinade B.I.D.
Conjec-B Robitussin A-C
Contac 12-Hour Robitussin Night Relief
Contac Day Caplets Robitussin Night Relief
Contac Maximum Strength Colds Formula Liquid
12-Hour Caplets Robitussin w/Codeine
Contac Night Caplets Rondec
Contac Severe Cold Formula Rondec Drops
Contac Severe Cold Formula Rondec-DM
Night Strength Rondec-DM Drops
Cophene No. 2 Rondec-TR
Cophene-B R-Tannate
Cophene-S Ru-Tuss
Cophene-X Ru-Tuss II
Cophene-XP Ru-Tuss w/Hydrocodone Liquid
Co-Pyronil 2 Ryna
Coricidin D Ryna-C Liquid
Coricidin Demilets Rynatan
Coricidin Maximum Strength Rynatuss
Sinus Headache Rynatuss Pediatric
Corcidin w/Codeine Salphenyl
Coristex-DH Scot-tussin Original 5-Action
Coristine-DH Cold Medicine
Corsym Seldane-D
CoTylenol Cold Medication Silphen
Covangesic Sinapils
Cremacoat 4 Throat Coating Sinarest
Cough Medicine Sinarest Extra Strength
CYPROHEPTADINE Sine-Off Maximum Strength
Dallergy Jr. Allergy/Sinus Formula
Dallergy-D Sine-Off Sinus Medicine
Dapacin Cold Singlet
Decohist Sinubid
Deconamine Sinucon Pediatric Drops
Deconamine SR Sinulin
Decongestabs Sinusol-B
Dehist Sinutab
Demazin Sinutab Extra Strength
Demazin Repetabs Sinutab Maximum Strength
Dexaphen SA Sinutab Regular
Dexchlor Sleep-Eze 3
Dexbrompheniramine Snaplets-D
Dexophed Sominex Liquid
Diahist Statuss Expectorant
Diamine T.D. Statuss Green
Dihistine Sudafed Plus
Dihistine DH Tamine S.R.
Dihydrex Tavist
Dimaphen S.A. Tavist-1
Dimentabs T-Dry
Dimetane T-Dry Junior
Dimetane-DC Cough Tega-Vert
Dimetane Decongestant Telachlor
Dimetane Decongestant Teldrin
Caplets TheraFlu/Flu & Cold
Dimetane-DX Cough TheraFlu/Flu, Cold & Cough
Dimetane Expectorant TheraFlu Nighttime Maximum
Dimetane Expectorant-C Strength
Dimetane Expectorant-DC Thera-Hist
Dimetane Extentabs T-Koff
Dimetane-Ten Touro A&H
Dimetapp Travamine
Dimetapp-A Triacin C Cough
Dimetapp-DM Triaminic
Dimetapp Extentabs Triaminic Allergy
Dimetapp Maximum Strength Triaminic Chewables
Liquigels Triaminic Cold
Dimetapp Oral Infant Drops Triaminic Expectorant
Dimetapp Plus Caplets Triaminic Expectorant DH
Dimetapp w/Codeine Triaminic Nite Light
Dinate Triaminic Oral Infant Drops
Diphen Cough Triaminic TR
Diphenacen-10 Triaminic-12
Diphenacen-50 Triaminic-DM Expectorant
Diphenadryl Triaminicin
DIPHENHYDRAMINE Triaminicin w/Codeine
Disobrom Triaminicol Multi-Symptom
Disophrol Relief
Disophrol Chronotabs Tricodene Forte
Dommanate Tricodene NN
Donatussin Tricom Tablets
Donatussin Drops Trifed
Dondril Trifed-C Cough
Dorcol Children's Trimedine Liquid
Cold Formula Trinalin Repetabs
Dormarex 2 Trind
Dormin Trind DM Liquid
DOXYLAMINE Tri-Nefrin Extra Strength
Dramamine Trinex
Dramamine Chewable Triofed
Dramamine Liquid Triotann
Dramanate Tripaigin Cold
Dramilin Trip-Tone
Dramoject Tri-Phen-Chlor
Dristan Tri-Phen-Chlor T.D.
Dristan AF Triphenyl
Dristan Cold Triphenyl T.D.
Dristan Cold and Flu Tripodrine
Dristan Formula P Triposed
Drixoral Plus Tritann Pediatric
Drixtab Trymegen
Drize Tusquelin
Duadacin Tuss-Ornade Spansules
Duralex Tussafed
Dura-Tap PD Tussagesic
Dura-Vent/A Tussaminic DH Forte
Dymenate Tussaminic DH Pediatric
EDA-Hist Tussanil DH
E-Vista Tussanil Plain
Effervescent Tylenol Cold Tussar DM
Efficol Cough Whip (Cough Tussar SF
Suppressant/Decongestant/ Tussar-2
Antihistamine) Tussionex
Efricon Expectorant Liquid Tussirex w/Codeine Liquid
Endafed Tusstat
Endal HD Twilite
Endal-HD Plus Ty-Cold Cold Formula
Extreme Cold Formula Caplets Tylenol Allergy Sinus Gelcaps
Father John's Medicine Plus Tylenol Cold and Flu
Fedahist Tylenol Cold Medication
Fedahist Decongestant Tylenol Cold Night Time
Fedahist Gyrocaps Unisom Nighttime Sleep Aid
Fedahist Timecaps Valdrene
Fenylhist Vanex-HD
Flogesic Vasominic T.D.
Fynex Veltane
Genac Veltap
Genallerate Vicks Formula 44 Cough
Genamin Mixture
Genatap Viro-Med
Gencold Vistaject
Gen-D-phen Vistaril
Gentab LA Vistazine
Gravol Wehamine
Gravol L/A Wehdryl
Guistrey Fortis Wehdryl-10
Hismanal Wehdryl-50

Basic Information

  • Habit forming? No
  • Prescription needed? High strength: Yes Low strength: No
  • Available as generic? Yes
  • Drug class: Antihistamine


  • Reduces allergic symptoms such as hay fever, hives, rash or itching.
  • Prevents motion sickness, nausea, vomiting.
  • Induces sleep.
  • Reduces stiffness and tremors of Parkinson's disease.

Dosage & Usage Information

How to take:
Follow label directions.

When to take:
Varies with form. Follow label directions.

If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Blocks action of histamine after an allergic response triggers histamine release in sensitive cells.

Time lapse before drug works:
30 minutes.

Don't take with:
Any other medicine without consulting your doctor or pharmacist.


Convulsions, red face, hallucinations, coma.


  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • See EMERGENCY Information.

Possible Adverse Reactions or Side Effects


    In case of overdose, see Overdose section.


    Drowsiness; dizziness; dry mouth, nose, throat; nausea.


  • Change in vision, clumsiness, rash.
  • Less tolerance for contact lenses, painful or difficult urination.
  • Appetite loss.


    Nightmares, agitation, irritability, sore throat, fever, rapid heartbeat, unusual bleeding or bruising, fatigue, weakness, confusion.

Warnings & Precautions

Don't take if:
You are allergic to any antihistamine.

Before you start, consult your doctor:

  • If you have glaucoma.
  • If you have enlarged prostate.
  • If you have asthma.
  • If you have kidney disease.
  • If you have peptic ulcer.
  • If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.

Over age 60:
Don't exceed recommended dose. Adverse reactions and side effects may be more frequent and severe than in younger persons, especially urination difficulty, diminished alertness and other brain and nervous-system symptoms.

No proven harm to unborn child. Avoid if possible.

Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine. Consult doctor for advice on maintaining milk supply.

Infants & children:
Not recommended for premature or newborn infants. Otherwise, no problems expected.

Prolonged use:
Avoid. May damage bone marrow and nerve cells.

Skin & sunlight:
May cause rash or intensify sunburn in areas exposed to sun or sunlamp.

Driving, piloting or hazardous work:
Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes, such as antihistamines, tranquilizers, sedatives, pain medicine, narcotics and mind-altering drugs.

No problems expected.


  • May mask symptoms of hearing damage from aspirin, other salicylates, cisplatin, paromomycin, vancomycin or anticonvulsants. Consult doctor if you use these.
  • Advise any doctor or dentist whom you consult that you take this medicine.

Possible Interaction with Other Drugs

------------------------ -----------------------
Anticholinergics* Increased anticholinergic effect.
Anticoagulants*, Decreased anti-
oral histamine effect.
Antidepressants* Excess sedation. Avoid.
Antihistamines, Excess sedation.
other* Avoid.
Carteolol Decreased antihistamine effect.
Central nervous May increase sedation.
Clozapine Toxic effect on the central nervous
Dronabinol Increased effects of both drugs.
Erythromycin Increased risk of toxicity with
Hypnotics* Excess sedation. Avoid.
Itraconazole Increased risk of cardiac toxicity
and death with astemizole.
MAO inhibitors* Increased antihistamine effect.
Mind-altering drugs* Excess sedation. Avoid.
Molindone Increased sedative and
antihistamine effect.
Nabilone Greater depression of central
nervous system.
Narcotics* Excess sedation. Avoid.
Procarbazine May increase sedation.
Sedatives* Excess sedation. Avoid.
Sertraline Increased depressive effects of both
Sleep inducers* Excess sedation. Avoid.
Sotalol Increased antihistamine effect.
Tranquilizers* Excess sedation. Avoid.

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: Excess sedation. Avoid.
Caffeine drinks. Less antihistamine sedation.
Cocaine: Decreased antihistamine effect.
Foods: None expected.
Marijuana: Excess sedation. Avoid.
Tobacco: None expected.

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