Diseases Symptoms Drugs Injuries Surgeries Vitamins Pediatric Symptoms
  home         about us         support center         contact us         terms of service         site map

VALPROIC ACID (Dipropylacetic Acid)

Brand & Generic Names

Myproic Acid

Basic Information

  • Habit forming? No
  • Prescription needed? Yes
  • Available as generic? Yes
  • Drug class: Anticonvulsant


  • Controls petit mal (absence) seizures in treatment of epilepsy.
  • Treatment for manic-depressive illness.

Dosage & Usage Information

How to take:
Capsule or syrup--Swallow with liquid or food to lessen stomach irritation.

When to take:
Once a day.

If you forget a dose:
Take as soon as you remember. Don't ever double dose.

What drug does:
Increases concentration of gamma aminobutyric acid, which inhibits nerve transmission in parts of brain.

Time lapse before drug works:
1 to 4 hours.

Don't take with:
Any other medicine without consulting your doctor or pharmacist.




  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • If patient is unconscious and not breathing, give mouth-to- mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). Don't try to make patient vomit. If you can't get help quickly, take patient to nearest emergency facility.
  • See EMERGENCY Information.

Possible Adverse Reactions or Side Effects


    In case of overdose, see Overdose section.


    Menstrual irregularities, nausea, vomiting, abdominal cramps, diarrhea, tremor, weight gain.


  • Rash, blood spots under skin, hair loss, bleeding (heart and lungs), easy bruising.
  • Sleepiness, weakness, easily upset emotionally, depression, psychic changes, headache, incoordination, appetite change, constipation.


  • Double vision, unusual movements of eyes (nystagmus), swelling of feet, ankles and abdomen; jaundice; increased bleeding tendency.
  • Anemia (paleness, fatigue).

Warnings & Precautions

Don't take if:
You are allergic to valproic acid.

Before you start, consult your doctor:

  • If you have blood, kidney or liver disease.
  • If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons.

Risk to unborn child exists. Don't use.

Unknown effect. Consult doctor.

Infants & children:
Under close medical supervision only.

Prolonged use:
Request periodic blood tests, liver and kidney function tests.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes, such as antihistamines, tranquilizers, sedatives, pain medicine, narcotics and mind-altering drugs.

Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment.

No problems expected.

Possible Interaction with Other Drugs

------------------------ -----------------------
Anticoagulants* Increased chance of bleeding.
Aspirin Increased chance of bleeding.
Carbamazepine Decreased valproic acid effect.
Central nervous Increased sedative
system (CNS) effect.
Clonazepam May prolong seizure.
Clozapine Toxic effect on bone marrow.
Didanosine Increased risk of pancreatitis.
Dipyridamole Increased chance of bleeding.
Felbamate Increased side effects and
adverse reactions.
Flecainide Possible decreased blood cell
production in bone marrow.
Hepatotoxics* Increased risk of liver toxicity.
Isoniazid Increased risk of liver damage.
Levocarnitine Decreased levocarnitine. Patients
taking valproic acid may need to
take the supplement levocarnitine.
MAO inhibitors* Increased sedative effect.
Mefloquine Decreased valproic acid effect.
Nabilone Greater depression of central
nervous system.
Phenobarbital Increases chance of toxicity.
Phenytoin Unpredictable. Dose may require
Primidone Increased chance of toxicity.
Sertraline Increased depressive effects
of both drugs.
Sodium benzoate May reduce effect of sodium benzoate
& sodium phenylacetate & sodium phenylacetate.
Sulfinpyrazone Increased chance of bleeding.
Tiopronin Increased risk of toxicity to bone
Tocainide Possible decreased blood cell
production in bone marrow.

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: Deep sedation. Avoid.
Beverages: No problems expected.
Cocaine: Increased brain sensitivity. Avoid.
Foods: No problems expected.
Marijuana: Increased brain sensitivity. Avoid.
Tobacco: Decreased valproic acid effect.

Dserun mollit anim id est laborum. Lorem ipsum and sunt in culpa qui officias deserunt mollit. Excepteur plus sint occaecat the best cupidatat nonr proident, sunt in culpa qui officia deserunt mollit anim id est laborum. September 24, 2004
read more


Excepteur plus sint occaecat the best cupidatat nonr proident, sunt in culpa qui officia deserunt mollit.
Support forums
Help desk
home       about us      affiliates     contact us       terms of service      

© 2005 All right reserved