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Brand & Generic Names

Arrestin Tegamide
Benzacot Ticon
Bio-Gan Tigan
Stemetic Tiject-20
T-Gen Triban
Tebamide Tribenzagan

Basic Information

  • Habit forming? No
  • Prescription needed? Yes
  • Available as generic? Yes
  • Drug class: Antiemetic


    Reduces nausea and vomiting.

Dosage & Usage Information

How to take:
Capsule--Swallow with liquid. If you can't swallow whole, open capsule and take with liquid or food.
Suppositories--Remove wrapper and moisten suppository with water. Gently insert larger end into rectum. Push well into rectum with finger.

When to take:
When needed, no more often than label directs.

If you forget a dose:
Take when you remember. Wait as long as label directs for next dose.

What drug does:
Possibly blocks nerve impulses to brain's vomiting centers.

Time lapse before drug works:
20 to 40 minutes.

Don't take with:
Any prescription or non-prescription drugs without consulting doctor.


Confusion, convulsions, coma.


  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • If patient is unconscious and not breathing, give mouth-to- mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). Don't try to make patient vomit. If you can't get help quickly, take patient to nearest emergency facility.
  • See EMERGENCY Information.

Possible Adverse Reactions or Side Effects


    In case of overdose, see Overdose section.


    None expected.


  • Rash, blurred vision, low blood pressure.
  • Dizziness, headache, drowsiness, diarrhea, muscle cramps, unusual tiredness.


  • Convulsions.
  • Seizures, tremor, depression, sore throat, fever, repeated vomiting, back pain, jaundice, Parkinson* symptoms, neck spasms.

Warnings & Precautions

Don't take if:

  • You are allergic to trimethobenzamide.
  • You are allergic to local anesthetics and have suppository form.

Before you start, consult your doctor:
If you have reacted badly to antihistamines.

Over age 60:
More susceptible to low blood pressure and sedative effects of this drug.

No proven harm to unborn child. Avoid if possible. Consult doctor.

No proven problems. Avoid if possible. Consult doctor.

Infants & children:

  • Injectable form not recommended.
  • Avoid during viral infections. Drug may contribute to Reye's syndrome.

Prolonged use:

  • Damages blood-cell production of bone marrow.
  • Causes Parkinson's-like symptoms of tremors, rigidity.

Skin & sunlight:
Possible sun sensitivity. Use caution.

Driving, piloting or hazardous work:

  • Use disqualifies you for piloting aircraft.
  • Don't drive until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes, such as antihistamines, tranquilizers, sedatives, pain medicine, narcotics and mind-altering drugs.

May be unnecessary to finish medicine. Follow doctor's instructions.

No problems expected.

Possible Interaction with Other Drugs

------------------------ -----------------------
Antidepressants* Increased sedative effect.
Antihistamines* Increased sedative effect.
Barbiturates* Increased effect of both drugs.
Belladonna Increased effect of both drugs.
Cholinergics* Increased effect of both drugs.
Clozapine Toxic effect on the central nervous
Ethinamate Dangerous increased effects of
ethinamate. Avoid combining.
Fluoxetine Increased depressant effects of
both drugs.
Guanfacine May increase depressant effects of
either medicine.
Leucovorin High alcohol content of leucovorin
may cause adverse effects.
Methyprylon May increase sedative effect to
dangerous level. Avoid.
Mind-altering drugs* Increased effect of mind-altering
Nabilone Greater depression of central
nervous system.
Narcotics* Increased sedative effect.
Phenothiazines* Increased effect of both drugs.
Sedatives* Increased sedative effect.
Sertraline Increased depressive effects of
both drugs.
Sleep inducers* Increased effect of sleep inducer.
Tranquilizers* Increased sedative effect.

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: Oversedation. Avoid.
Beverages: None expected.
Cocaine: None expected.
Foods: None expected.
Marijuana: Increased antinausea effect.
Tobacco: None expected.

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