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Brand & Generic Names


Basic Information

  • Habit forming? Yes
  • Prescription needed? Yes
  • Available as generic? Yes
  • Drug class: Sedative (hypnotic)


  • Treatment for insomnia.
  • Prevention or treatment of transient insomnia associated with sudden sleep schedule changes such as travel across several time zones.

Dosage & Usage Information

How to take:
Tablet: Swallow with liquid. If you can't swallow whole, crumble tablet and take with liquid or food.

When to take:
At the same time each day, according to instructions on prescription label.

If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Affects limbic system of brain, the part that controls emotions.

Time lapse before drug works:
2 hours. May take 6 weeks for full benefit.

Don't take with:
Any prescription or non-prescription drugs without consulting you doctor.


Drowsiness, weakness, tremor, stupor, coma.


  • Dial O (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately.
  • If patient is unconscious and not breathing, give mouth-to-mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). Don't try to make patient vomit. If you can't get help quickly, take patient to nearest emergency facility.
  • See Emergency Information.

Possible Adverse Reactions or Side Effects


    In case of overdose, see Overdose section above.


    Clumsiness, drowsiness, dizziness.


  • Amnesia, hallucinations, confusion, depression, irritability, rash, itch, vision changes, sore throat, fever, chills, dry mouth.
  • Constipation or diarrhea, nausea, vomiting, difficult urination, vivid dreams, behavior changes, abdominal pain, headache.


  • Slow heartbeat, breathing difficulty.
  • Mouth, throat ulcers; jaundice.
  • Decreased sex drive.

Warnings & Precautions

Don't take if:

  • You are allergic to any benzodiazepine.
  • You have myasthenia gravis.
  • You are an active or recovering alcoholic.
  • Patient is younger than 6 months.

Before you start, consult your doctor:

  • If you have liver, kidney or lung disease.
  • If you have diabetes, epilepsy or porphyria.
  • If you have glaucoma.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons. You may need smaller doses for shorter periods of time. You may develop agitation, rage or a 'hangover' effect.

Risk to unborn child outweighs drug benefits. Don't use.

Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine. Consult doctor for advice on maintaining milk supply.

Infants & children:
Use only under medical supervision for children older than 6 months.

Prolonged use:
May impair liver function.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes.

Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment.


  • Hot weather, heavy exercise and profuse sweat may reduce excretion and cause overdose.
  • Blood sugar may rise in diabetics, requiring insulin adjustment.
  • Don't use for insomnia more than 4-7 days.
  • Advise any doctor or dentist whom you consult that you take this medicine.
  • Triazolam has a very short duration of action in the body.

Possible Interaction with Other Drugs

------------------------ -----------------------
Anticonvulsants* Change in seizure frequency
or severity.
Antidepressants* Increased sedative effect of
both drugs.
Antihistamines* Increase sedative effect of
both drugs.
Antihypertensives* Excessively low blood pressure.
Cimetidine Increased triazolam effect.
Clozapine Toxic effect on the central nervous
Contraceptives*, oral Increased triazolam effect.
Disulfiram Increased triazolam effect.
Dronabinol Increased effects of both drugs.
Erythromycins* Increased triazolam effect.
Isoniazid Increased triazolam effect.
Ketoconazole Increased triazolam effect.
Levodopa Possible decreased levodopa effect.
MAO inhibitors* Convulsions, deep sedation, rage.
Molindone Increased tranquilizer effect.
Nabilone Greater depression of central nervous
Narcotics* Increased sedative effect of both drugs.
Nicotine Increased triazolam effect.
Nizatidine Increased effect and toxicity of
Omeprazole Delayed excretion of triazolam causing
increased amount of triazolam in blood.
Probenecid Increased triazolam effect.
Sedatives* Increased sedative effect of both drugs.
Sleep inducers* Increased sedative effect of both drugs.
Tranquilizers* Increased sedative effect of both drugs.
Zidovudine Increased toxicity of zidovudine.

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: Heavy sedation. Avoid.
Beverages: None expected.
Cocaine: Decreased triazolam effect.
Foods: None expected.
Marijuana: Heavy sedation. Avoid.
Tobacco: Decreased triazolam effect.

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