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Brand & Generic Names

Azma Aid T.E.P.
Phedral-C.T. Theodrine
Primatene "P" Formula Theodrine Pediatric
Tedral Theofed
Tedral SA Theofedral

Basic Information

  • Habit forming? Yes
  • Prescription needed? Some yes, others no
  • Available as generic? Some yes, others no
  • Drug class: Bronchodilator, barbiturate, sympathomimetic, sedative


  • Treatment for bronchial asthma symptoms.
  • Decreases congestion of breathing passages.
  • Suppresses allergic reactions.
  • Reduces anxiety or nervous tension (low dose).

Dosage & Usage Information

How to take:
Tablet or elixir--Swallow with liquid.
Extended-release tablets--Swallow each dose whole. If you take regular tablets, you may chew or crush them.

When to take:
Most effective taken on empty stomach 1 hour before or 2 hours after eating. However, may take with food to lessen stomach upset.

If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Relaxes and expands bronchial tubes.
Prevents cells from releasing allergy-causing chemicals (histamines).
Decreases blood vessel size and blood flow, thus causing decongestion.
May partially block nerve impulses at nerve-cell connections.

Time lapse before drug works:
15 to 30 minutes.

Don't take with:
Non-prescription drugs with ephedrine, pseudoephedrine or epinephrine.
Non-prescription drugs for cough, cold, allergy or asthma without consulting doctor.
Any other medicine without consulting your doctor or pharmacist.


Restlessness, irritability, anxiety, confusion, hallucinations, vomiting blood, delirium, muscle tremors, convulsions, rapid and irregular pulse, coma.


  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • See EMERGENCY Information.

Possible Adverse Reactions or Side Effects


    Difficult breathing, Discontinue. Seek uncontrollable rapid emergency treatment. heart rate, loss of consciousness.


  • Headache, irritability, nervousness, restlessness, insomnia, nausea, vomiting, abdominal pain, irregular heartbeat, "hangover" effect.
  • Dizziness, light- headedness, paleness, heartburn.


  • Rash; hives; red or flushed face; appetite loss; diarrhea; cough; confusion; slurred speech; eyelid, face, lip swelling; joint pain.
  • Frequent urination.


    Agitation; sore throat, fever, mouth sores; jaundice.

Warnings & Precautions

Don't take if:

  • You are allergic to any bronchodilator or barbiturate.
  • You are allergic to ephedrine or any sympathomimetic* drug.
  • You have an active peptic ulcer or porphyria.

Before you start, consult your doctor:

  • If you have gastritis, peptic ulcer, high blood pressure or heart disease, diabetes, overactive thyroid gland, difficulty urinating, epilepsy, kidney or liver damage, asthma, anemia, chronic pain.
  • If you have taken any MAO inhibitor in past 2 weeks, taken digitalis preparations in the last 7 days.
  • If you have had impaired kidney or liver function.
  • If you take medication for gout.
  • If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.

Over age 60:

  • Adverse reactions and side effects may be more frequent and severe than in younger persons. Use small doses.
  • More likely to develop high blood pressure, heart rhythm disturbances, angina and to feel drug's stimulant effects.

Risk to unborn child outweighs drug benefits. Don't use.

Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine.

Infants & children:
Use only under medical supervision.

Prolonged use:

  • Stomach irritation.
  • Excessive doses--Rare toxic psychosis.
  • Men with enlarged prostate gland may have more urination difficulty.
  • May cause addiction, anemia, chronic intoxication.
  • May lower body temperature, making exposure to cold temperatures hazardous.

Skin & sunlight:
May cause rash or intensify sunburn in areas exposed to sun or sunlamp.

Driving, piloting or hazardous work:
Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes.


  • May be unnecessary to finish medicine. Follow doctor's instructions.
  • If you develop withdrawal symptoms of hallucinations, agitation or sleeplessness after discontinuing, call doctor right away.

Potential for abuse.

Possible Interaction with Other Drugs

------------------------ -----------------------
Allopurinol Decreased allopurinol effect.
Anticoagulants*, Decreased anticoagulant effect.
Anticonvulsants* Changed seizure patterns.
Antidepressants, Decreased antidepressant effect.
tricyclic (TCA)* Possible dangerous oversedation.
Antidiabetics*, Increased phenobarbital effect.
oral effect.
Antihistamines* Dangerous sedation. Avoid.
Antihypertensives* Decreased antihypertensive effect.
Aspirin Decreased aspirin effect.
Beta-adrenergic Decreased effect of drugs.
Carteolol Increased barbiturate effect.
Dangerous sedation.
Ciprofloxacin Increased possibility of central
nervous system poisoning, such as
nausea, vomiting, restlessness,
Clarithromycin Increased concentration of
Contraceptives*, Decreased contraceptive
oral effect.
Cortisone drugs* Decreased cortisone effect.
Digitalis Serious heart rhythm
preparations* disturbances.
Doxycycline Decreased doxycycline effect.
Dronabinol Increased effect of drugs. Avoid.
Ephedrine Increased effect of drugs.
Epinephrine Increased effect of drugs.
Ergot preparations* Serious blood pressure rise.
Erythromycins* Increased bronchodilator effect.
Finasteride Decreased theophylline effect.
Furosemide Increased furosemide effect.
Griseofulvin Decreased griseofulvin effect.
Guanethidine Decreased effect of drugs.
Indapamide Increased indapamide effect.
Lincomycins* Increased bronchodilator effect.
Lithium Decreased lithium effect.
MAO inhibitors* Increased ephedrine effect.
Dangerous blood pressure rise.
Mind-altering drugs* Dangerous sedation. Avoid.
Narcotics* Dangerous sedation. Avoid.
Nicardipine May increase theophylline effect
and toxicity.
Nicotine Increased bronchodilator effect.
Nitrates* Possible decreased effect of drugs.
Non-steroidal Decreased anti-inflammatory
anti-inflammatory effect.
Probenecid Decreased effect of drugs.
Propranolol Decreased bronchodilator effect.
Pseudoephedrine Increased pseudoephedrine effect.
Rauwolfia alkaloids* Rapid heartbeat.
Sotalol Increased barbiturate effect.
Dangerous sedation.
Sulfinpyrazone Decreased sulfinpyrazone effect.
Terazosin Decreased effect of terazosin.
Ticlopidine Increased theophylline effect.
Troleandomycin Increased bronchodilator effect.
Valproic acid Increased barbiturate effect.

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: Possible fatal oversedation. Avoid.
Caffeine drinks. Nervousness or insomnia.
Cocaine: High risk of heartbeat
irregularities and high blood
Foods: None expected.
Marijuana: Rapid heartbeat, possible heart-
rhythm disturbance.
Tobacco: Decreased bronchodilator effect.

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