Diseases Symptoms Drugs Injuries Surgeries Vitamins Pediatric Symptoms
  home         about us         support center         contact us         terms of service         site map


Brand & Generic Names


Basic Information

  • Habit forming? No
  • Prescription needed? Yes
  • Available as generic? No
  • Drug class: Antibiotic (rifamycin)


    Treatment for tuberculosis and other infections. Requires daily use for 1 to 2 years.

Dosage & Usage Information

How to take:
Capsule--Swallow with liquid. If you can't swallow whole, open capsule and take with liquid or small amount of food. For child, mix with small amount of applesauce or jelly.

When to take:
1 hour before or 2 hours after a meal.

If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Prevents multiplication of tuberculosis germs.

Time lapse before drug works:
Usually 2 weeks. May require 1 to 2 years without missed doses for maximum benefit.

Don't take with:
Any other medicine without consulting your doctor or pharmacist.


Slow, shallow breathing; weak, rapid pulse; cold, sweaty skin; coma.


  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • If patient is unconscious and not breathing, give mouth-to- mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). Don't try to make patient vomit. If you can't get help quickly, take patient to nearest emergency facility.
  • See EMERGENCY Information.

Possible Adverse Reactions or Side Effects


    In case of overdose, see Overdose section.


    Diarrhea; reddish urine, stool, saliva, sweat and tears.


  • Rash; flushed, itchy skin of face and scalp; blurred vision; difficult breathing; nausea, vomiting; abdominal cramps.
  • Dizziness, unsteady gait, confusion, muscle or bone pain, heartburn, flatulence, chills.
  • Headache, fever.


  • Sore throat, mouth or tongue; jaundice.
  • Appetite loss, less urination.

Warnings & Precautions

Don't take if:

  • You are allergic to rifampin.
  • You wear soft contact lenses.

Before you start, consult your doctor:
If you are alcoholic or have liver disease.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons.

Studies inconclusive on harm to unborn child. Animal studies show fetal abnormalities. Decide with your doctor whether drug benefits justify risk to unborn child.

No proven problems. Consult doctor.

Infants & children:
Use only under medical supervision.

Prolonged use:

  • You may become more susceptible to infections caused by germs not responsive to rifampin.
  • Talk to your doctor about the need for follow-up medical examinations or laboratory studies to check liver function.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes, such as antihistamines, tranquilizers, sedatives, pain medicine, narcotics and mind-altering drugs.

Don't discontinue without doctor's advice until you complete prescribed dose, even though symptoms diminish or disappear.

Reddish tears may discolor soft contact lenses.

Possible Interaction with Other Drugs

------------------------ -----------------------
Anticoagulants*, Decreased anticoagulant effect.
Antidiabetics*, Decreased antidiabetic effect.
Barbiturates* Decreased barbiturate effect.
Chloramphenicol Decreased effect of both drugs.
Clozapine Toxic effect on bone marrow.
Contraceptives*, Decreased contraceptive
oral effect.
Cortisone drugs* Decreased effect of cortisone
Cyclosporine Decreased effect of both drugs.
Dapsone Decreased dapsone effect.
Digitoxin Decreased digitoxin effect.
Disopyramide Decreased disopyramide effect.
Estrogens* (including Decreased effect of both drugs.
Flecainide Possible decreased blood cell
production in bone marrow.
Isoniazid Possible toxicity to liver.
Itraconazole Decreased itraconazole effect.
Ketoconazole Decreased ketoconazole effect.
Methadone Decreased methadone effect.
Mexiletine Decreased mexiletine effect.
Nicardipine Decreased nicardipine effect.
Nimodipine Decreased nimodipine effect.
Para-aminosalicylic Decreased rifampin
acid effect.
Phenytoin Decreased phenytoin effect.
Probenecid Possible toxicity to liver.
Quinidine Decreased effect of both drugs.
Theophyllines* Decreased theophylline effect.
Tiopronin Increased risk of toxicity to bone
marrow and kidneys.
Tocainide Possible decreased blood cell
production in bone marrow.
Tolbutamide Decreased tolbutamide effect.
Trimethoprim Decreased trimethoprim effect.

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: Possible toxicity to liver.
Beverages: None expected.
Cocaine: No proven problems.
Foods: None expected.
Marijuana: No proven problems.
Tobacco: None expected.

Dserun mollit anim id est laborum. Lorem ipsum and sunt in culpa qui officias deserunt mollit. Excepteur plus sint occaecat the best cupidatat nonr proident, sunt in culpa qui officia deserunt mollit anim id est laborum. September 24, 2004
read more


Excepteur plus sint occaecat the best cupidatat nonr proident, sunt in culpa qui officia deserunt mollit.
Support forums
Help desk
home       about us      affiliates     contact us       terms of service      

© 2005 All right reserved