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Brand & Generic Names

Legatrin Quindan
NovoQuinine Quiphile
Quin-260 Q-Vel
Quin-amino Strema

Basic Information

  • Habit forming? No
  • Prescription needed? High strength: Yes Low strength: No
  • Available as generic? Yes
  • Drug class: Antiprotozoal


  • Treatment or prevention of malaria.
  • Relief of muscle cramps.

Dosage & Usage Information

How to take:
Tablet or capsule--Swallow with liquid or food to lessen stomach irritation.

When to take:
Prevention--At the same time each day, usually at bedtime.
Treatment--At the same times each day in evenly spaced doses.

If you forget a dose:
Prevention--Take as soon as you remember up to 12 hours late. If more than 12 hours, wait for next scheduled dose (don't double this dose).
Treatment--Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Reduces contractions of skeletal muscles.
Increases blood flow.
Interferes with genes in malaria micro-organisms.

Time lapse before drug works:
May require several days or weeks for maximum effect.

Don't take with:
Any other medicine without consulting your doctor or pharmacist.


Severe impairment of vision and hearing; severe nausea, vomiting, diarrhea; shallow breathing, fast heartbeat; apprehension, confusion, delirium.


    Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.

Possible Adverse Reactions or Side Effects


    In case of overdose, see Overdose section.


  • Blurred vision or change in vision, eyes sensitive to light.
  • Dizziness, headache, abdominal discomfort, mild nausea, vomiting, diarrhea.
  • Ringing or buzzing in ears, impaired hearing.


    Rash, hives, itchy skin, difficult breathing.


    Sore throat, fever, unusual bleeding or bruising, unusual tiredness or weakness, angina.

Warnings & Precautions

Don't take if:
You are allergic to quinine or quinidine.

Before you start, consult your doctor:

  • If you plan to become pregnant within medication period.
  • If you have asthma.
  • If you have eye disease, hearing problems or ringing in the ears.
  • If you have heart disease.
  • If you have myasthenia gravis.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons.

Risk to unborn child outweighs drug benefits. Don't use.

Drug filters into milk. May harm child. Avoid.

Infants & children:
Use only under medical supervision.

Prolonged use:
May develop headache, blurred vision, nausea, temporary hearing loss, but seldom need to discontinue because of these symptoms.

Skin & sunlight:
Increased sensitivity to sunlight.

Driving, piloting or hazardous work:
Avoid if you feel dizzy or have blurred vision. Otherwise, no problems expected.

Don't discontinue without doctor's advice until you complete prescribed dose, even though symptoms diminish or disappear.

Don't confuse with quinidine, a medicine for heart rhythm problems.

Possible Interaction with Other Drugs

------------------------ -----------------------
Alkalizers*, urinary Possible toxic effects of quinine.
Antacids* (with Decreased quinine effect.
Anticoagulants*, Increased anticoagulant effect.
Dapsone Increased risk of adverse effect
on blood cells.
Digitalis Possible increased digitalis
Digoxin Possible increased digoxin effect.
Mefloquine Increased risk of heartbeat
Quinidine Possible toxic effects of quinine.

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: No proven problems.
Beverages: None expected.
Cocaine: No proven problems.
Foods: None expected.
Marijuana: No proven problems.
Tobacco: None expected.

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