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Brand & Generic Names

Actacin Maximum Strength Tylenol
Actagen Allergy Sinus Caplets
Actagen-C Cough Medi-Flu
Actifed Medi-Flu Caplets
Actifed A Mediquell Decongestant
Actifed Plus Formula
Actifed Plus Caplets Midahist DH
Actifed w/Codeine Cough Mycotussin
Actifed DM Myfed
Actifed 12-Hour Myfedrine
Afrinol Repetabs Myfredine Plus
Alamine-C Liquid Myhistine DH
Alamine Expectorant Myhistine Expectorant
Allent Mytussin DAC
Allerest No-Drowsiness Naldegesic
Allerfrin Allergy Formula Napril
Sinutab ND Clear T.D.
Allerfrin w/Codeine Neofed
AlleRid Noratuss II Liquid
Allerphed Novafed
Alpha-Phed Novafed A
Ambenyl-D Decongestant Novahistex
Cough Novahistine Cough &
Anamine Cold Formula Liquid
Anamine T.D. Novahistine DH Liquid
Anaplex Novahistine DMX Liquid
Aprodrine Novahistine Expectorant
Atrofed Formula Nucochem
Balminil Decongestant Nucochem Expectorant
BayCotussend Liquid Nucochem Pediatric
Baydec DM Drops Expectorant
Bayer Select Maximum Nucofed
Strength Sinus Pain Nucofed Expectorant
Relief Caplets Nucofed Pediatric
Bayhistine DH Expectorant
Bayhistine Expectorant NyQuil Hot Therapy
Benadryl Allergy/Sinus NyQuil Liquicaps
Headache Caplets NyQuil Nighttime Colds
Benadryl Decongestant Medicine
Benadryl Plus Nytime Cold Medicine
Benadryl Plus Nighttime Liquid
Liquid Oral Suspension Ornex Cold
Benylin Cold Ornex No Drowsiness
Benylin Decongestant Caplets
Beta-Phed Otrivin
Brexin PediaCare Children's Cough-
Brexin-L.A. Cold Formula
Bromfed PediaCare Children's Cold
Bromfed-AT Relief Night Rest
Bromfed-DM Cough-Cold Formula
Bromphed-PD PediaCare Cold Formula
Brompheril PediaCare Infants' Oral
Brotane DX Cough Decongestant Drops
Carbinoxamine Compound Pertussin AM
Carbiset Pertussin PM
Carbodec Phenapap Sinus Headache
Carbodec DM Drops & Congestion
Carbodec TR Phenergan-D
Cardec-S Phenhist Expectorant
Cenafed Polaramine Expectorant
Cenafed Plus Promist HD Liquid
Cheracol Sinus Pseudo
Children's NyQuil Nighttime Pseudo-Bid
Cold Medicine Pseudo-Car DM
Children's Sudafed Liquid Pseudo-Chlor
Children's Tylenol Cold Pseudodine C Cough
Chlorafed Pseudofrin
Chlorafed H.S. Timecelles Pseudogest
Chlorafed Timecelles Pseudogest Plus
Chlor-Trimeton Decongestant Pseudo-Hist Expectorant
Chlor-Trimeton Decongestant Respaire-60 SR
Repetabs Respaire-120 SR
Chlor-Trimeton Non-Drowsy Resporal TR
Decongestant 4 Hour Rhinosyn-DM
Chlor-Tripolon Decongestant Rhinosyn-X
Extra Strength Rinade B.I.D.
Chlor-Tripolon Decongestant Robidrine
Tablets Robitussin-DAC
Chlor-Tripolon Decongestant Robitussin Night Relief
Repetabs Robitussin-PE
Claritin Extra Rondec
CoActifed Rondec Drops
CoActifed Expectorant Rondec-DM
CoAdvil Rondec-DM Drops
CoAdvil Caplets Ru-Tuss Expectorant
Co-Apap Rymed-TR
Codehist DH Ryna
Codimal Ryna-C Liquid
Codimal-LA Ryna-CX Liquid
Coldrine Seldane D
Comtrex A/S Sinarest No-Drowsiness
Comtrex Daytime Caplets Sine-Aid
Comtrex Hot Flu Relief Sine-Aid Maximum Strength
Comtrex Multi-Symptom Sine-Aid Maximum Strength
Hot Flu Relief Caplets
Comtrex Multi-Symptom Sine-Off Maximum Strength
Non-Drowsy Caplets Allergy/Sinus Formula
Comtrex Nighttime Sine-Off Maximum Strength
Concentrin No Drowsiness Formula
Congess JR Caplets
Congess SR Singlet
Congestac N.D. Caplets Sinufed Timecelles
Contac Day Caplets Sinus Excedrin No Drowsiness
Contac Maximum Strength Sinus Excedrin No Drowsiness
Sinus Caplets Caplets
Contac Night Caplets SinuStat
Contac Severe Cold Formula Sinutab
Contac Severe Cold Formula Sinutab II Maximum Strength
Night Strength Sinutab Extra Strength
Cophene No. 2 Sinutab Maximum Strength
Co-Pyronil 2 Sinutab Maximum Strength
CoTylenol Cold Medication Without Drowsiness
Cremacoat 3 Throat Coating Sinutab Maximum Strength
Cough Medicine Without Drowsines Caplets
Cremacoat 4 Throat Coating Sinutab No Drowsiness
Cough Medicine Sinutab No Drowsiness
C-Tussin Expectorant Extra Strength
Dallergy-D Sinutab Regular
Dallergy Jr. SRC Expectorant
DayCare Stamoist E
DayQuil Liquicaps Sudafed
DayQuil Non-Drowsy Cold/Flu Sudafed 12 Hour
Decofed Sudafed 60
Deconamine Sudafed Cough
Deconamine SR Sudafed DM
DeFed-60 Sudafed Expectorant
Deproist Expectorant Sudafed Plus
w/Codeine Sudafed Severe Cold
De-Tuss Formula Caplets
Detussin Expectorant Sudafed Sinus Maximum
Detussin Liquid Strength
Dexaphen SA Sudafed Sinus Maximum
Dexophed Strength Caplets
Dihistine DH Sudrin
Dimacol Sufedrin
Dimetane-DX Cough Super-Anahist
Dimetapp Sinus Caplets TheraFlu/Flu & Cold
Disobrom TheraFlu/Flu, Cold &
Disophrol Cough
Disophrol Chronotabs TheraFlu Nighttime Maximum
Dorcol Children's Cold Strength
Formula Thera-Hist
Dorcol Children's Cough T-Dry
Dorcol Children's T-Dry Junior
Decongestant T-Moist
Dristan Cold and Flu Touro A&H
Dristan Juice Mix-in Cold, Triacin C Cough
Flu, and Cough Triaminic Nite Light
Dristan Maximum Strength Tricom Caplets
Caplets Trifed
Dristan Sinus Caplets Trifed-C Cough
Drixoral Trinalin Repetabs
Drixoral Non-Drowsy Formula Trinex
Drixoral Plus Triofed
Drixoral Sinus Tripodrine
Drixtab Triposed
Duralex Tussafed
Dura-Tap PD Tussar DM
Duratuss Tussend
Duratuss HD Tussend Expectorant
Efidec/24 Tussend Liquid
Eltor-120 Tuss-LA
Endafed Ty-Cold Cold Formula
Entuss-D Tylenol Allergy Sinus
Entuss Pediatric Gelcaps
Expectorant Tylenol Cold and Flu
Fedahist Tylenol Cold Medication
Fedahist Decongestant Tylenol Cold Medication,
Fedahist Expectorant Non-Drowsy
Fedahist Expectorant Tylenol Cold Night Time
Pediatric Drops Tylenol Cold No Drowsiness
Fedahist Gyrocaps Gelcaps
Fedahist Timecaps Tylenol Cough
Genac Tylenol Cough with
Genaphed Decongestant
Guaifed Tylenol Sinus Maximum
Guaifed-PD Strength
Guaimax-D Tylenol Sinus Maximum
Guaitab Strength Caplets
Halofed Tylenol Sinus Maximum
Halofed Adult Strength Strength Gelcaps
Head & Chest Tylenol Sinus Medication
Histadyl E.C. Tylenol Sinus Medication
Histafed C Extra Strength
Histalet Ursinus Inlay
Histalet-DM Vicks Formula 44D
Histalet X Decongestant Cough
Isoclor Mixture
Isoclor Expectorant Vicks Formula 44M Multi-
Isoclor Timesules symptom Cough Mixture
Klerist-D Viro-Med
Kronofed-A Zephrex
Kronofed-A Jr. Zephrex-LA
Maximum Strength Dristan
Cold Multi-Symptom Caplets

Basic Information

  • Habit forming? No
  • Prescription needed? U.S.: High strength--Yes Low strength--No Canada: No
  • Available as generic? Yes
  • Drug class: Sympathomimetic


    Reduces congestion of nose, sinuses, eustachian tubes and throat from allergies and infections.

Dosage & Usage Information

How to take:
Tablet--Swallow with liquid. You may chew or crush tablet.
Extended-release capsules--Swallow each dose whole.
Syrup--Take as directed on label.
Drops--Place directly on tongue and swallow.

When to take:
At the same times each day.
To prevent insomnia, take last dose of day a few hours before bedtime.

If you forget a dose:
Take up to 2 hours late. If more than 2 hours, wait for next dose (don't double this dose).

What drug does:
Decreases blood volume in nasal tissues, shrinking tissues and enlarging airways.

Time lapse before drug works:
15 to 20 minutes.

Don't take with:
Non-prescription drugs with caffeine without consulting doctor.
Any other medicine without consulting your doctor or pharmacist.


Nervousness, restlessness, headache, rapid or irregular heartbeat, sweating, nausea, vomiting, anxiety, confusion, delirium, muscle tremors, convulsions, hallucinations.


  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • See EMERGENCY Information.

Possible Adverse Reactions or Side Effects


    In case of overdose, see Overdose section.


    Agitation, insomnia.


  • Nausea or vomiting, irregular or slow heartbeat, difficult breathing, unusually fast or pounding heartbeat, painful or difficult urination, increased sweating, trembling.
  • Dizziness, headache, shakiness, weakness.
  • Paleness.


    Hallucinations, seizures.

Warnings & Precautions

Don't take if:
You are allergic to any sympathomimetic drug.

Before you start, consult your doctor:

  • If you have overactive thyroid or diabetes.
  • If you have taken any MAO inhibitors in past 2 weeks.
  • If you take digitalis preparations or have high blood pressure or heart disease.
  • If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.
  • If you have urination difficulty.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons.

No proven harm to unborn child. Avoid if possible. Consult doctor.

Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine. Consult doctor for advice on maintaining milk supply.

Infants & children:
Keep dose low or avoid.

Prolonged use:
No proven problems.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
Avoid if you feel dizzy. Otherwise, no problems expected..

May be unnecessary to finish medicine. Follow doctor's instructions.

No problems expected.

Possible Interaction with Other Drugs

------------------------ -----------------------
Antihypertensives* Decreased antihypertensive effect.
Beta-adrenergic Decreased effect of both
blockers* drugs.
Calcium supplements* Increased pseudoephedrine effect.
Digitalis Irregular heartbeat.
Epinephrine Increased epinephrine effect.
Excessive heart stimulation and
blood pressure increase.
Ergot preparations* Serious blood pressure rise.
Guanadrel Decreased effect of both drugs.
Guanethidine Decreased effect of both drugs.
MAO inhibitors* Increased pseudoephedrine effect.
Methyldopa Possible increased blood pressure.
Nitrates* Possible decreased effects of both
Phenothiazines* Possible increased pseudoephedrine
toxicity. Possible decreased
pseudoephedrine effect.
Rauwolfia Decreased rauwolfia effect.
Sympathomimetics* Increased pseudoephedrine effect.
Terazosin Decreases effectiveness of

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: None expected.
Caffeine drinks. Nervousness or insomnia.
Cocaine: High risk of heartbeat
irregularities and high blood
Foods: None expected.
Marijuana: Rapid heartbeat.
Tobacco: None expected.

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