Brand & Generic Names
- Habit forming? No
- Prescription needed? Yes
- Available as generic? No
- Drug class: Antihyperlipidemic
Lowers cholesterol level in blood in persons with type IIa
Dosage & Usage Information
How to take:
Tablet--Swallow with liquid. If you can't swallow whole, crumble
tablet and take with liquid or food.
When to take:
With morning and evening meals.
If you forget a dose:
Take as soon as you remember up to 2 hours
late. If more than 2 hours, wait for next scheduled dose (don't
double this dose).
What drug does:
Reduces serum cholesterol without reducing liver cholesterol.
Time lapse before drug works:
3 to 4 months.
Don't take with:
Other medicines or vitamins. Separate by 1 to 2 hours.
WHAT TO DO:
Overdose unlikely to threaten life. If person takes much larger
amount than prescribed, call doctor, poison-control center or
hospital emergency room for instructions.
Possible Adverse Reactions or Side Effects
abdominal pain, flatus.
- Dizziness, headache.
- Numbness or tingling
in feet, toes,
- Swelling of hands,
face, feet, mouth.
Warnings & Precautions
Don't take if:
You are allergic to probucol.
Before you start, consult your doctor:
- If you have liver disease such as cirrhosis.
- If you have heartbeat irregularity.
- If you have congestive heart failure that is not under
- If you have gallstones.
Over age 60:
Adverse reactions and side effects may be more frequent and
severe than in younger persons.
No proven problems. Avoid if possible. Continue using birth-
control methods for 6 months after discontinuing medicine.
Not recommended. Animal studies show drug passes into milk.
Studies not available for human beings. Consult doctor.
Infants & children:
Not recommended. Safety and dosage have not been established.
Request serum cholesterol and serum triglyceride laboratory
studies every 2 to 4 months.
Skin & sunlight:
No problems expected.
Driving, piloting or hazardous work:
If medicine does not cause dizziness, no problems expected.
Don't discontinue without consulting doctor. Dose may require
gradual reduction if you have taken drug for a long time. Doses
of other drugs may also require adjustment.
- Medicine works best in conjunction with low-fat, low-cholesterol
diet and an active, regular exercise program.
- May affect results in some medical test.
Possible Interaction with Other Drugs
||Decreased chenodiol effect.
||Combination no more effective than
||one drug only, so don't take both.
Possible Interaction with Other Substances
||May aggravate liver problems.