Sitename.com
Diseases Symptoms Drugs Injuries Surgeries Vitamins Pediatric Symptoms
  home         about us         support center         contact us         terms of service         site map

PRIMIDONE


Brand & Generic Names

Apo-Primidone
Myidone
Mysoline
PMS Primadone
Sertan


Basic Information

  • Habit forming? No
  • Prescription needed? Yes
  • Available as generic? Yes
  • Drug class: Anticonvulsant

Uses

    Prevents some forms of epileptic seizures.

Dosage & Usage Information

How to take:
Tablet--Swallow with liquid. If you can't swallow whole, crumble tablet and take with liquid or food.
Liquid--If desired, dilute dose in beverage before swallowing.

When to take:
Daily in regularly spaced doses, according to doctor's prescription.

If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Probably inhibits repetitious spread of impulses along nerve pathways.

Time lapse before drug works:
2 to 3 weeks.

Don't take with:
Any other medicine without consulting your doctor or pharmacist.


Overdose

SYMPTOMS:
Slow, shallow breathing; weak, rapid pulse; confusion, deep sleep, coma.

WHAT TO DO:

  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • If patient is unconscious and not breathing, give mouth-to- mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). Don't try to make patient vomit. If you can't get help quickly, take patient to nearest emergency facility.
  • See EMERGENCY Information.

Possible Adverse Reactions or Side Effects

Life-threatening:

    In case of overdose, see Overdose section.

Common:

  • Difficult breathing.
  • Confusion, change in vision.
  • Clumsiness, dizziness, drowsiness.

Infrequent:

  • Unusual excitement, particularly in children; nausea; vomiting.
  • Headache, fatigue, weakness.

Rare:

  • Rash or hives, appetite loss, acute psychosis, hair loss, fever, joint pain.
  • Swollen eyelids or legs.
  • Decreased sexual ability.

Warnings & Precautions

Don't take if:

  • You are allergic to any barbiturate.
  • You have had porphyria.

Before you start, consult your doctor:

  • If you have had liver, kidney or lung disease or asthma.
  • If you have lupus.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons.

Pregnancy:
Studies inconclusive on harm to unborn child. Animal studies show fetal abnormalities. Decide with your doctor whether drug benefits justify risk to unborn child.

Breast-feeding:
Drug filters into milk. May harm child. Avoid. Consult doctor.

Infants & children:
Use only under medical supervision.

Prolonged use:

  • Enlarged lymph and thyroid glands.
  • Anemia.
  • Rickets in children and osteomalacia (insufficient calcium to bones) in adults.
  • Talk to your doctor about the need for follow-up medical examinations or laboratory studies to check complete blood counts (white blood cell count, platelet count, red blood cell count, hemoglobin, hematocrit), liver function, kidney function.

Skin & sunlight:
None expected.

Driving, piloting or hazardous work:
Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes.

Discontinuing:
Don't discontinue abruptly or without doctor's advice until you complete prescribed dose, even though symptoms diminish or disappear.

Others:

  • Tell doctor if you become ill or injured and must interrupt dose schedule.
  • Periodic laboratory blood tests of drug level recommended.

Possible Interaction with Other Drugs

GENERIC NAME COMBINED EFFECT
------------------------ -----------------------
Anticoagulants*, Decreased primidone effect.
Anticonvulsants*, Changed seizure pattern.
Antidepressants* Increased antidepressant effect.
Antidiabetics* Increased sedation effect of
primidone.
Antihistamines* Increased sedation effect of
primidone.
Aspirin Decreased aspirin effect.
Carbamazepine Unpredictable increase or decrease
of primidone effect.
Carbonic anhydrase Possible decreased primidone effect.
Central nervous system Increased CNS depressant effects.
Contraceptives*, Decreased contraceptive effect.
Cortisone drugs* Decreased cortisone effect.
Cyclosporine Decreased effect of cyclosporine.
Digitalis Decreased digitalis effect.
Disulfiram Possible increased primidone
effect.
Estrogens* Decreased estrogen effect.
Griseofulvin Possible decreased griseofulvin
effect.
Isoniazid Decreased primidone effect.
Leucovorin May counteract anticonvulsant
(large dose) effect of primidone.
Loxapine Decreased anticonvulsant effect of
primidone.
MAO inhibitors* Increased sedation effect of
primidone.
Metronidazole Possible decreased metronidazole
effect.
Mind-altering drugs* Increased effect of mind-altering
drugs.
Nabilone Greater depression of central
nervous system.
Narcotics* Increased narcotic effect.
Oxyphenbutazone Decreased oxyphenbutazone effect.
Phenylbutazone Decreased phenylbutazone effect.
Phenytoin Possible increased primidone
toxicity.
Rifampin Possible decreased primidone
effect.
Sedatives* Increased sedative effect.
Sertraline Increased depressive effects
of both drugs.
Sleep inducers* Increased effect of sleep inducer.
Tranquilizers* Increased tranquilizer effect.


Possible Interaction with Other Substances

INTERACTS WITH COMBINED EFFECT
--------------- ---------------
Alcohol: Dangerous sedative effect. Avoid.
Beverages: None expected.
Cocaine: Decreased primidone effect.
Foods: Possible need for more vitamin D.
Marijuana: Decreased anticonvulsant effect of
primidone. Drowsiness,
unsteadiness.
Tobacco: None expected.



Dserun mollit anim id est laborum. Lorem ipsum and sunt in culpa qui officias deserunt mollit. Excepteur plus sint occaecat the best cupidatat nonr proident, sunt in culpa qui officia deserunt mollit anim id est laborum. September 24, 2004
read more

Email:

Excepteur plus sint occaecat the best cupidatat nonr proident, sunt in culpa qui officia deserunt mollit.
Support forums
Help desk
F.A.Q.
go
home       about us      affiliates     contact us       terms of service      

© 2005 HealthSE.com All right reserved