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PHENYLPROPANOLAMINE


Brand & Generic Names

12-Hour Cold Kiddy Koff
Alamine Kolephrin/DM
Alka-Seltzer Plus Cold Kolephrin NN Liquid
Alka-Seltzer Plus Maximum Kophane
Strength Sinus Allergy Kophane Cough and Cold
Alka-Seltzer Plus Maximum Formula
Strength Sinus Allergy Lanatuss Expectorant
Medicine Medatussin Plus
Alka-Seltzer Plus Myhydromine
Nighttime Cold Myhydromine Pediatric
Allerest Myminic
Allerest 12 Hour Allergy Myphetane DC Cough
Relief Medicine Myphetapp
Allerest Headache Strength Naldecon
Allerest Sinus Pain Formula Naldecon Pediatric
Alumadrine Naldecon-CX Adult Liquid
Amaril D Naldecon-DX Adult Liquid
Ami-Tex LA Naldecon-DX Children's Syrup
Anatuss Naldecon-DX Pediatric Drops
Anatuss with Codeine Naldecon-EX
A.R.M. Maximum Strength Naldelate
Caplets Naldelate Pediatric Syrup
BC Cold Powder Nalgest
BC Cold Powder Non-Drowsy Nasahist
Formula New-Decongest
Banex New-Decongest Pediatric Syrup
Banex Liquid Nolamine
Banex-LA Nolex LA
Bayaminic Expectorant Noraminic
Bayaminicol Norel Plus
Baycomine Normatane
Baycomine Pediatric Normatane DC
Bayer Cough Syrup Oragest S.R.
Bayer Cough Syrup for Oraminic Spancaps
Children Ornade
Biphetane DC Cough Syrup Ornade A.F.
BQ Cold Ornade-DM
Bromanate DC Cough Syrup Ornade-DM 10
Bromatap Ornade-DM 15
Bromatapp Ornade-DM 30
Bromophen T.D. Ornade Expectorant
Bromphen DC w/Codeine Cough Orthoxicol Cough
Caldomine-DH Forte Panadyl
Caldomine-DH Pediatric Par Decon
Cheracol Plus Pertussin AM
Chexit Phanadex
Chlor-Rest PhenAPAP No. 2
Chlor-Trimetron Sinus Caplets Phenate T.D.
Chlor-Tripolon Decongestant Phentox Compound
Codamine Phenylfenesin L.A.
Codamine Pediatric Poly-Histine-CS
Codegest Expectorant Poly-Histine-D
Codimal Expectorant Poly-Histine-D Ped
Comtrex Multi-Symptom Poly-Histine-DM
Cold Reliever Prominic Expectorant
Condrin-LA Prominicol Cough
Conex Pyrroxate
Conex D.A. Remcol Cold
Conex Plus Rentamine
Conex w/Codeine Liquid Resaid S.R.
Congesprin for Children Rescaps-D S.R.
Liquid Cold Medicine Respinol-G
Contac Jr. Children's Respinol LA
Cold Medicine Rhinocaps
Contac 12-Hour Rhinolar-EX
Contac Maximum Strength Rhinolar-EX 12
12-Hour Robitussin-CF
Contac Maximum Strength Ru-Tuss II
12-Hour Caplets Ru-Tuss w/Hydrocodone
Cophene-S Liquid
Cophene-X Rymed
Cophene-XP Rymed Liquid
Coricidin Cough Saleto-CF
Coricidin D Saleto-D
Coricidin D Decongestant Sinapils
Coricidin D Medilets Sinarest
Coricidin Demilets Sinarest Extra Strength
Coricidin Maximum Strength Sine-Off Sinus Medicine
Sinus Headache Sinubid
Corsym Sinucon Pediatric Drops
Dapacin Cold Sinulin
Decongestabs Sinutab SA
Dehist Snaplets-D
Demazin Snaplets-DM
Demazin Repetabs Snaplets-EX
Despec Snaplets-Multi
Dilotab St. Joseph Cold Tablets
Dimaphen S.A. for Children
Dimetane Expectorant Stamoist LA
Dimetane Expectorant-C Statuss Green
Dimetane Expectorant-DC Syracol Liquid
Dimetane-DC Cough Tamine S.R.
Dimetapp Tavist-D
Dimetapp-A T-Koff
Dimetapp-A Pediatric Triaminic
Dimetapp-DM Triaminic Allergy
Dimetapp with Codeine Triaminic Chewables
Dimetapp Extentabs Triaminic Cold
Dimetapp Maximum Strength Triaminic-DM Cough Formula
Liquigels Triaminic-DM Expectorant
Dimetapp Oral Infant Drops Triaminic Expectorant
Dimetapp Plus Caplets Triaminic Expectorant DH
Dorcol DM Triaminic Expectorant
Drinophen w/Codeine
Dristan Triaminic Oral Infant Drops
Drize Triaminic TR
Duadacin Triaminicin
Dura-Vent Triaminicin w/Codeine
Dura-Vent/A Triaminicol DM
Effervescent Tylenol Cold Triaminicol Multi-Symptom
Efficol Cough Whip (Cough Relief
Suppressant/Decongestant) Tricodene Forte
Efficol Cough Whip (Cough Tricodene NN
Suppressant/Decongestant/ Tricodene NN Pediatric
Antihistamine) Medication
Efficol Whip Tricodene Pediatric
Entex Trind
Entex LA Trind DM Liquid
Entex Liquid Tri-Nefrin Extra Strength
Extreme Cold Formula Caplets Tripalgen Cold
Flogesic Tri-Phen-Chlor
Genamin Tri-Phen-Chlor T.D.
Genatap Triphenyl
Gencold Triphenyl Expectorant
Genex Triphenyl T.D.
Gentab-LA Tusquelin
Guaipax Tuss-Ade
Halls Mentho-Lyptus Tussagesic
Halls Mentho-Lyptus Tuss Allergine Modified
Decongestant Cough T.D.
Formula Tussaminic C Forte
Head & Chest Tussaminic C Pediatric
Histabid Duracaps Tussaminic DH Forte
Histalet Forte Tussaminic DH Pediatric
Histamic Tussanil DH Tablets
Hista-Vadrin Tussogest
Histosal Tuss-Ornade Liquid
Hold (Children's Formula) Tuss-Ornade Spansules
Hycomine Tylenol Cold Medicine
Hycomine Pediatric ULR-LA
Hydromine Utex-S.R.
Hydromine Pediatric Vasominic T.D.
Hydrophen Veltap
Ipsatol Cough Formula
for Children


Basic Information

  • Habit forming? No
  • Prescription needed? High strength: Yes Low strength: No
  • Available as generic? Yes
  • Drug class: Sympathomimetic

Uses

  • Relieves bronchial asthma.
  • Decreases congestion of breathing passages.
  • Suppresses allergic reactions.
  • Decreases appetite.
  • Treatment for urinary incontinence.

Dosage & Usage Information

How to take:
Tablet--Swallow with liquid. You may chew or crush tablet.
Extended-release capsules--Swallow each dose whole.

When to take:
As needed, no more often than every 4 hours.

If you forget a dose:
Take up to 2 hours late. If more than 2 hours, wait for next dose (don't double this dose).

What drug does:
Prevents cells from releasing allergy-causing chemicals (histamines).
Relaxes muscles of bronchial tubes.
Decreases blood vessel size and blood flow, thus causing decongestion.

Time lapse before drug works:
30 to 60 minutes.

Don't take with:
Non-prescription drugs for cough, cold, allergy or asthma without consulting doctor.
See Interaction Section and consult doctor.


Overdose

SYMPTOMS:
Severe anxiety, confusion, delirium, muscle tremors, rapid and irregular pulse.

WHAT TO DO:

  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • See EMERGENCY Information.

Possible Adverse Reactions or Side Effects

Life-threatening:

    In case of overdose, see Overdose section.

Common:

  • Rapid heartbeat.
  • Nervousness, headache, paleness.
  • Insomnia.

Infrequent:

  • Irregular heartbeat.
  • Dizziness, appetite loss, nausea, vomiting, difficult urination, nightmares, weakness.

Rare:

    Tightness in chest.

Warnings & Precautions

Don't take if:
You are allergic to any sympathomimetic* drug.

Before you start, consult your doctor:

  • If you have high blood pressure, diabetes, overactive thyroid gland, difficulty urinating.
  • If you have taken any MAO inhibitors in past 2 weeks.
  • If you have taken digitalis preparations in the last 7 days.
  • If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.
  • If you take any other over-the-counter medicine.

Over age 60:
More likely to develop high blood pressure, heart rhythm disturbances and angina and to feel drug's stimulant effects.

Pregnancy:
Safety not established. Decide with your doctor if drug benefits justify risk to unborn child.

Breast-feeding:
Safety not established. Consult doctor.

Infants & children:
Don't give to children under 6 years old.

Prolonged use:

  • Excessive doses--Rare toxic psychosis.
  • Men with enlarged prostate gland may have more urination difficulty.
  • Talk to your doctor about the need for follow-up medical examinations or laboratory studies.

Skin & sunlight:
No known problems.

Driving, piloting or hazardous work:
No restrictions unless you feel dizzy.

Discontinuing:
May be unnecessary to finish medicine. Follow doctor's instructions.

Others:
No problems expected.


Possible Interaction with Other Drugs

GENERIC NAME COMBINED EFFECT
------------------------ -----------------------
Anesthetics*, Increased phenylpropanolamine
general effect.
Antidepressants, Increased effect of phenylpropanolamine.
tricyclic (TCA)* Excessive stimulation of heart and
blood pressure.
Antihypertensives* Decreased antihypertensive effect.
Beta-adrenergic Decreased effects of
blockers* both drugs.
Digitalis Serious heart rhythm
preparations* disturbances.
Epinephrine Increased epinephrine effect.
Ergot preparations* Serious blood pressure rise.
Guanethidine Decreased effect of both drugs.
Guanadrel Decreased effect of both drugs.
MAO inhibitors* Increased phenylpropanolamine
effect. Dangerous blood pressure
rise.
Methyldopa Possible increased blood pressure.
Nitrates* Possible decreased effects of both
drugs.
Phenothiazines* Possible increased phenylpropanolamine
toxicity. Possible decreased
phenylpropanolamine effect.
Rauwolfia Decreased rauwolfia effect.
Sympathomimetics* Increased phenylpropanolamine
effect.
Terazosin Decreases effectiveness of
terazosin.


Possible Interaction with Other Substances

INTERACTS WITH COMBINED EFFECT
--------------- ---------------
Alcohol: Increased sedation.
Caffeine drinks. Nervousness or insomnia.
Cocaine: High risk of heartbeat
irregularities and high blood
pressure.
Foods: None expected.
Marijuana: Rapid heartbeat, possible heart
rhythm disturbance. Avoid.
Tobacco: None expected.



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