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PHENYLEPHRINE


Brand & Generic Names

Aclophen Hycomine
Advanced Formula Dristan Hycomine Compound
Advanced Formula Dristan Hycomine-S Pediatric
Caplets Improved Sino-Tuss
Alersule Kolephrin
Amaril D Korigesic
Amaril D Spantab Mallergan-VC w/Codeine
Anamine HD Meda Syrup Forte
Anatuss Myhistine
Atrohist Sprinkle Naldecon
Banex Naldecon Pediatric
Banex Liquid Naldelate
Bromophen T.D. Nalgest
Cerose-DM Nasahist
Citra Forte ND-Gesic
Chlorgest-HD Neo Citran Sinus Medicine
Codimal DH New-Decongest
Codimal DM New-Decongest Pediatric
Codimal PH Syrup
Colrex Compound Normatane
Colrex Cough Novahistex C
Coltab Children's Novahistex DH
Comhist Novahistex DH Expectorant
Comhist LA Novahistex DM
Conar Novahistine
Conar Expectorant Novahistine DH
Conar-A Novahistine DH Expectorant
Congespirin for Children Omnicol
Cold Tablets P-V-Tussin
Cophene-S Par Decon
Cophene-X Pediacof Cough
Cophene-XP Phenameth VC
Coristex-DH Phenameth VC w/Codeine
Coristine-DH Phenergan VC
Covangesic Phenergan VC w/Codeine
Dallergy-D Syrup Phentox Compound
Decohist Pherazine VC
Decongestabs Pherazine VC w/Codeine
Despec Prometh VC Plain
Dihistine Prometh VC w/Codeine
Dimaphen S.A. Promethazine VC
Dimetane Decongestant Quelidrine Cough
Caplets Respinol G
Dimetane Expectorant Respinol LA
Dimetane Expectorant-C Rhinogesic
Dimetane Expectorant-DC Robitussin Night Relief
Dimetapp-A Robitussin Night Relief
Dimetapp-A Pediatric Colds Formula Liquid
Dimetapp Elixir R-Tannate
Dimetapp Oral Infant Drops Ru-Tuss
Dimetapp with Codeine Ru-Tuss w/Hydrocodone
Dimetapp-DM Ru-Tuss Expectorant
Donatussin Ru-Tuss w/Hydrocodone
Donatussin DC Liquid
Donatussin Drops Rymed
Dondril Rymed Liquid
Dristan-AF Rynatan
Dristan-AF Plus Salphenyl
Dristan Cold Scot-Tussin
Dristan Formula P Sinucon Pediatric Drops
EDA-HIST Statuss Expectorant
Efricon Expectorant Liquid Statuss Green
Endal-HD Tamine S.R.
Endal-HD Plus T-Koff
Entex Trimedine Liquid
Entex Liquid Triotann
Father John's Medicine Plus Tri-Phen-Chlor
Fendol Tri-Phen-Chlor T.D.
Guistrey Fortis Tritann Pediatric
Histagesic Modified Tusquelin
Histalet Forte Tussanil DH
Histamic Tussanil Plain
Histatab Tussirex w/Codeine
Histatan Tussirex w/Codeine Liquid
Histatuss Pediatric Vanex-HD
Hista-Vadrin Vasominic T.D.
Histor-D Veltap
Histussin HC


Basic Information

  • Habit forming? No
  • Prescription needed? No
  • Available as generic? Yes
  • Drug class: Sympathomimetic

Uses

  • Temporary relief of congestion of nose, sinuses and throat caused by allergies, colds or sinusitis.
  • Treats congestion of eustachian tubes caused by middle ear infections.

Dosage & Usage Information

How to take:
According to package directions.

When to take:
As needed, no more often than every 4 hours.

If you forget a dose:
Take when you remember. Wait 4 hours for next dose. Never double a dose.

What drug does:
Contracts blood vessel walls of nose, sinus and throat tissues, enlarging airways.

Time lapse before drug works:
5 to 30 minutes.

Don't take with:
Non-prescription drugs for asthma, cough, cold, allergy, appetite suppressants, sleeping pills or drugs containing caffeine without consulting doctor.
See Interaction Section and consult doctor.


Overdose

SYMPTOMS:
Headache, heart palpitations, vomiting, blood pressure rise, slow and forceful pulse.

WHAT TO DO:

  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • See EMERGENCY Information.

Possible Adverse Reactions or Side Effects

Life-threatening:

    In case of overdose, see Overdose section.

Common:

  • Fast or pounding heartbeat.
  • Headache or dizziness; shakiness; insomnia; burning, dryness, stinging inside nose; nervousness.

Infrequent:

    Paleness.

Rare:

    Unusual sweating.

Warnings & Precautions

Don't take if:
You are allergic to any sympathomimetic.

Before you start, consult your doctor:

  • If you have high blood pressure.
  • If you have heart disease.
  • If you have diabetes.
  • If you have overactive thyroid.
  • If you have taken MAO inhibitors in past 2 weeks.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons.

Pregnancy:
Risk to unborn child outweighs drug benefits. Don't use.

Breast-feeding:
Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine. Consult doctor for advice on maintaining milk supply.

Infants & children:
Use only under close supervision.

Prolonged use:

  • Rebound* congestion and chemical irritation of nasal membranes.
  • May cause functional dependence.
  • Talk to your doctor about the need for follow-up medical examinations or laboratory studies to check blood pressure, ECG*.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
No problems expected.

Discontinuing:
May be unnecessary to finish medicine. Follow doctor's instructions.

Others:
No problems expected.


Possible Interaction with Other Drugs

GENERIC NAME COMBINED EFFECT
------------------------ -----------------------
Amphetamines* Increased nervousness.
Antiasthmatics* Nervous stimulation.
Antidepressants, Increased phenylephrine effect.
Antihypertensives* Decreased antihypertensive effect.
Beta-adrenergic Decreased effects of
blockers* both drugs.
Digitalis Decreased digitalis effect.
Furazolidine Sudden, severe increase in
blood pressure.
Guanadrel Decreased effect of both drugs.
MAO inhibitors* Dangerous blood pressure rise.
Methyldopa Possible increased blood pressure.
Nicotine Decreased phenylephrine effect.
Nitrates* Possible decreased effects of both
drugs.
Oxprenolol Decreased effects of both drugs.
Phenothiazines* Possible increased phenylephrine
toxicity. Possible decreased
phenylephrine effect.
Rauwolfia Decreased rauwolfia effect.
Sedatives* Decreased sedative effect.
Sympathomimetics*, Increased stimulant
other effect.
Tranquilizers* Decreased tranquilizer effect.


Possible Interaction with Other Substances

INTERACTS WITH COMBINED EFFECT
--------------- ---------------
Alcohol: None expected.
Caffeine drinks. Excess brain stimulation.
Cocaine: Excess brain stimulation.
Foods: None expected.
Marijuana: None expected.
Tobacco: None expected.



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