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Brand & Generic Names

4-Way Long Acting Nafrine Decongestant
Nasal Spray Nasal Spray
Afrin 12 Hour Nasal Spray Nafrine Decongestant Pedia-
Afrin 12 Hour Nose Drops tric Nasal Spray/Drops
Afrin Children's Strength Neo-Synephrine 12 Hour
12 Hour Nose Drops Nasal Spray
Afrin Children's Strength Neo-Synephrine 12 Hour
Nose Drops Nasal Spray Pump
Afrin Menthol Nasal Spray Neo-Synephrine 12
Afrin Nasal Spray Nose Drops
Afrin Nasal Spray Pump Neo-Synephrine 12 Hour
Afrin Nose Drops Vapor Nasal Spray
Allerest 12 Hour Nasal Nostrilla 12 Hour
Spray Nasal Decongestant
Coricidin Nasal Mist Nostril Nasal Decongestant
Dristan Long Lasting Mild
Menthol Nasal Spray Nostril Nasal Decongestant
Dristan Long Lasting Regular
Nasal Pump Spray NTZ Long Acting Decongest-
Dristan Long Lasting ant Nasal Spray
Nasal Spray NTZ Long Acting Decongest-
Dristan Long Lasting Nasal ant Nose Drops
Spray 12 Hour Metered Sinarest 12 Hour Nasal
Dose Pump Spray
Duramist Plus Up to 12 Vicks Sinex 12-Hour Formula
Hours Decongestant Nasal Decongestant Nasal Spray
Spray Vicks Sinex 12-Hour
Duration 12 Hour Nasal Formula Decongestant
Spray Pump Ultra Fine Mist
Nafrine Decongestant Vicks Sinex Long-Acting
Nasal Drops 12 Hour Nasal Spray

Basic Information

  • Habit forming? No
  • Prescription needed? No
  • Available as generic? Yes
  • Drug class: Sympathomimetic


    Relieves congestion of nose, sinuses and throat from allergies and infections.

Dosage & Usage Information

How to take:
Nasal solution, nasal spray--Use as directed on label. Avoid contamination. Don't use same container for more than 1 person.

When to take:
When needed, no more often than every 4 hours.

If you forget a dose:
Take as soon as you remember. Wait 4 hours for next dose.

What drug does:
Constricts walls of small arteries in nose, sinuses and eustachian tubes.

Time lapse before drug works:
5 to 30 minutes.

Don't take with:
Non-prescription drugs for allergy, cough or cold without consulting doctor.
Any other medicine without consulting your doctor or pharmacist.


Headache, sweating, anxiety, agitation, rapid and irregular heartbeat (rare occurrence with systemic absorption).


  • Dial 911 (emergency) or 0 (operator) for an ambulance or medical help. Then give first aid immediately.
  • If patient is unconscious and not breathing, give mouth-to-mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). If you can't get help quickly, take patient to nearest emergency facility.
  • See EMERGENCY information.

Possible Adverse Reactions or Side Effects


    In case of overdose, see previous section.


    None expected.


    Burning, dry or stinging nasal passages.


    Rebound congestion (increased runny or stuffy nose); headache, insomnia, nervousness (may occur with systemic absorption).

Warnings & Precautions

Don't take if:
You are allergic to any sympathomimetic nasal spray.

Before you start, consult your doctor:

  • If you have heart disease or high blood pressure.
  • If you have diabetes.
  • If you have overactive thyroid.
  • If you have taken MAO inhibitors in past 2 weeks.
  • If you have glaucoma.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons.

No proven harm to unborn child. Avoid if possible. Consult doctor.

No proven problems. Consult doctor.

Infants & children:
Don't give to children younger than 2.

Prolonged use:
Drug may lose effectiveness, cause increased congestion (rebound effect*) and irritate nasal membranes.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
No problems expected.

May be unnecessary to finish medicine. Follow doctor's instructions.

No problems expected.

Possible Interaction with Other Drugs

------------------------- -----------------------
Antidepressants, Possible rise in blood pressure.
Maprotiline Possible increased blood pressure.

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: None expected.
Caffeine drinks. Nervousness or insomnia.
Cocaine: High risk of heartbeat irregularities
and high blood pressure.
Foods: None expected.
Marijuana: Overstimulation. Avoid.
Tobacco: None expected.

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