Diseases Symptoms Drugs Injuries Surgeries Vitamins Pediatric Symptoms
  home         about us         support center         contact us         terms of service         site map


Brand & Generic Names


Basic Information

  • Habit forming? No
  • Prescription needed? Yes
  • Available as generic? Yes
  • Drug class: Antihypertensive


    Reduces high blood pressure.

Dosage & Usage Information

How to take:
Liquid or tablet--Swallow with liquid. If you can't swallow whole, crumble tablet and take with liquid or food.

When to take:
At the same times each day.

If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Relaxes walls of small arteries to decrease blood pressure.

Time lapse before drug works:
Continual use for 2 to 4 weeks may be necessary to determine effectiveness.

Don't take with:
Any other medicine without consulting your doctor or pharmacist.


Drowsiness; exhaustion; stupor; confusion; slow, weak pulse.


  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • If patient is unconscious and not breathing, give mouth-to- mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). Don't try to make patient vomit. If you can't get help quickly, take patient to nearest emergency facility.
  • See EMERGENCY Information.

Possible Adverse Reactions or Side Effects


    In case of overdose, see Overdose section.


    Depression, sedation, nightmares, headache, drowsiness, weakness, stuffy nose, dry mouth, fluid retention, swollen feet or legs.


  • Fast heartbeat, fainting.
  • Insomnia, nausea, vomiting, diarrhea, constipation, foot and hand numbness and tingling.
  • Swollen breasts, diminished sex drive.


    Rash, jaundice, dark urine, chills, breathing difficulty, unexplained fever, sore or "black" tongue, severe abdominal pain, decreased mental activity and memory impairment, facial paralysis, slow heartbeat, chest pain, swollen abdomen.

Warnings & Precautions

Don't take if:
You will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.

Before you start, consult your doctor:
If you have liver disease.

Over age 60:

  • Increased susceptibility to dizziness, unsteadiness, fainting, falling.
  • Drug can produce or intensify Parkinson's disease.

No proven problems. Consult doctor.

No proven problems. Consult doctor.

Infants & children:
Not used.

Prolonged use:

  • May cause anemia.
  • Severe edema (fluid retention).
  • Talk to your doctor about the need for follow-up medical examinations or laboratory studies to check complete blood counts (white blood cell count, platelet count, red blood cell count, hemoglobin, hematocrit), blood pressure, liver function.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes, such as antihistamines, tranquilizers, sedatives, pain medicine, narcotics and mind-altering drugs.

Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment.

Avoid heavy exercise, exertion, sweating.

Possible Interaction with Other Drugs

------------------------ -----------------------
ACE inhibitors*: Possible excessive potassium
captopril, enalapril, in blood.
Amphetamines* Decreased methyldopa effect.
Anticoagulants*, Increased anticoagulant effect.
Antidepressants, Dangerous blood pressure rise.
tricyclic (TCA)* Decreased methyldopa effect.
Antihypertensives* Increased antihypertensive effect.
Carteolol Increased antihypertensive effect.
Clozapine Toxic effect on the central nervous
Dapsone Increased risk of adverse effect on
blood cells.
Didanosine Increased risk of pancreatitis.
Digitalis Excessively slow heartbeat.
Diuretics, thiazide* Increased methyldopa effect.
Ethinamate Dangerous increased effects of
ethinamate. Avoid combining.
Fluoxetine Increased depressant effects of
both drugs.
Guanfacine May increase depressant effects of
either drug.
Haloperidol Increased sedation. Possibly
Isoniazid Increased risk of liver damage.
Leucovorin High alcohol content of leucovorin
may cause adverse effects.
Levodopa Increased effect of both drugs.
Loxapine May increase toxic effects of both
MAO inhibitors* Dangerous blood pressure rise.
Methyprylon Increased sedative effect, perhaps
to dangerous level. Avoid.
Nabilone Greater depression of central
nervous system.
Nicardipine Blood pressure drop. Dosages may
require adjustment.
Nimodipine Dangerous blood pressure drop.
Norepinephrine Decreased methyldopa effect.
Pergolide Decreased pergolide effect.
Phenoxybenzamine Urinary retention.
Phenylephrine Decreased methyldopa effect.
Phenylpropanolamine Decreased methyldopa effect.
Propranolol Increased blood pressure (rarely).
Sertraline Increased depressive effects of
both drugs.
Sotalol Increased antihypertensive effect.
Sympathomimetic drugs* Increased risk of heart block and
high blood pressure.
Terazosin Decreases effectiveness of
Tolbutamide Increased tolbutamide effect.

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: Increased sedation. Excessive blood
pressure drop. Avoid.
Beverages: None expected.
Cocaine: Increased risk of heart block and
high blood pressure.
Foods: None expected.
Marijuana: Possible fainting.
Tobacco: Possible increased blood pressure.

Dserun mollit anim id est laborum. Lorem ipsum and sunt in culpa qui officias deserunt mollit. Excepteur plus sint occaecat the best cupidatat nonr proident, sunt in culpa qui officia deserunt mollit anim id est laborum. September 24, 2004
read more


Excepteur plus sint occaecat the best cupidatat nonr proident, sunt in culpa qui officia deserunt mollit.
Support forums
Help desk
home       about us      affiliates     contact us       terms of service      

© 2005 All right reserved