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Brand & Generic Names

Apo-Haloperidol Halperon
Haldol Novo-Peridol
Haldol Decanoate Peridol
Haldol LA PMS-Haloperidol

Basic Information

  • Habit forming? No
  • Prescription needed? Yes
  • Available as generic? Yes
  • Drug class: Tranquilizer (antipsychotic)


  • Reduces severe anxiety, agitation and psychotic behavior.
  • Treatment for Tourette's syndrome.
  • Treatment for infantile autism.
  • Treatment for Huntington's chorea.

Dosage & Usage Information

How to take:
Tablet--Swallow with liquid. If you can't swallow whole, crumble tablet and take with liquid or food.
Drops--Dilute dose in beverage before swallowing.

When to take:
At the same times each day.

If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Corrects an imbalance in nerve impulses from brain.

Time lapse before drug works:
3 weeks to 2 months for maximum benefit.

Don't take with:
Non-prescription drugs without consulting doctor.
Any other medicine without consulting your doctor or pharmacist.


Weak, rapid pulse; shallow, slow breathing; tremor or muscle weakness; very low blood pressure; convulsions; deep sleep ending in coma.


  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • If patient is unconscious and not breathing, give mouth-to- mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). Don't try to make patient vomit. If you can't get help quickly, take patient to nearest emergency facility.
  • See EMERGENCY Information.

Possible Adverse Reactions or Side Effects


    Uncontrolled muscle Discontinue. Seek movements of tongue, emergency treatment. face and other muscles (neuroleptic malignant syndrome, rare).


  • Blurred vision, loss of balance, muscle spasms, severe restlessness.
  • Shuffling, stiffness, jerkiness, shakiness, constipation, weight gain.
  • Dry mouth.


  • Rash, circling motions of tongue, hallucinations, lip smacking.
  • Dizziness, faintness, drowsiness, difficult urination, decreased sexual ability, nausea or vomiting.


    Sore throat; fever; jaundice; abdominal pain; dry, warm skin.

Warnings & Precautions

Don't take if:

  • You have ever been allergic to haloperidol.
  • You are depressed.
  • You have Parkinson's disease.
  • Patient is younger than 3 years old.

Before you start, consult your doctor:

  • If you take sedatives, sleeping pills, tranquilizers, antidepressants, antihistamines, narcotics or mind-altering drugs.
  • If you have a history of mental depression.
  • If you have had kidney or liver problems.
  • If you have diabetes, epilepsy, glaucoma, high blood pressure or heart disease, prostate trouble.
  • If you drink alcoholic beverages frequently.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons.

Risk to unborn child outweighs drug benefits. Don't use.

Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine. Consult doctor about maintaining milk supply.

Infants & children:
Not recommended.

Prolonged use:

  • May develop tardive dyskinesia (involuntary movements of jaws, lips and tongue).
  • Talk to your doctor about the need for follow-up medical examinations or laboratory studies to check blood pressure, liver function.

Skin & sunlight:
May cause rash or intensify sunburn in areas exposed to sun or sunlamp.

Driving, piloting or hazardous work:
Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes.

Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment.

No problems expected.

Possible Interaction with Other Drugs

------------------------ -----------------------
Anticholinergics* Increased anticholinergic effect.
May cause pressure within the eye.
Anticonvulsants* Changed seizure pattern.
Antidepressants* Excessive sedation.
Antihistamines* Excessive sedation.
Antihypertensives* May cause severe blood pressure
Barbiturates* Excessive sedation.
Bupropion Increased risk of major seizures.
Central nervous system Increased CNS depression; increased
(CNS) depressants* blood pressure drop.
Clozapine Toxic effect on the
central nervous system.
Dronabinol Increased effects of both drugs.
Ethinamate Dangerous increased effects of
ethinamate. Avoid combining.
Fluoxetine Increased depressant effects of
both drugs.
Guanethidine Decreased guanethidine effect.
Guanfacine May increase depressant effects of
either drug.
Loxapine May increase toxic effects of both
Leucovorin High alcohol content of leucovorin
may cause adverse effects.
Levodopa Decreased levodopa effect.
Lithium Increased toxicity.
Methyldopa Possible psychosis.
Methyprylon Increased sedative effect, perhaps
to dangerous level. Avoid.
Nabilone Greater depression of central
nervous system.
Narcotics* Excessive sedation.
Pergolide Decreased pergolide effect.
Phenindione Decreased anticoagulant effect.
Procarbazine Increased sedation.
Sedatives* Excessive sedation.
Sertraline Increased depressive effects of
both drugs.
Tranquilizers* Excessive sedation.

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: Excessive sedation and depressed
brain function. Avoid.
Beverages: None expected.
Cocaine: Decreased effect of haloperidol.
Foods: None expected.
Marijuana: Occasional use--Increased sedation.
Frequent use--Possible toxic
Tobacco: None expected.

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