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Brand & Generic Names

Fulvicin P/G
Fulvicin U/F
Grifulvin V
Grisactin Ultra

Basic Information

  • Habit forming? No
  • Prescription needed? Yes
  • Available as generic? Yes
  • Drug class: Antibiotic (antifungal)


    Treatment for fungal infections susceptible to griseofulvin.

Dosage & Usage Information

How to take:
Tablet or capsule--Swallow with liquid or food to lessen stomach irritation. If you can't swallow whole, crumble tablet or open capsule and take with liquid or food.
Liquid--Follow label instructions.

When to take:
With or immediately after meals.

If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Prevents fungi from growing and reproducing.

Time lapse before drug works:
2 to 10 days for skin infections. 2 to 4 weeks for infections of fingernails or toenails. Complete cure of either may require several months.

Don't take with:
Any other medicine without consulting your doctor or pharmacist.


Nausea, vomiting, diarrhea. In sensitive individuals, severe diarrhea may occur without overdosing.


    Overdose unlikely to threaten life. If person takes much larger amount than prescribed, call doctor, poison-control center or hospital emergency room for instructions.

Possible Adverse Reactions or Side Effects


    In case of overdose, see Overdose section.




  • Confusion; rash, hives, itch; mouth or tongue irritation; soreness; nausea; vomiting; diarrhea; stomach pain.
  • Insomnia, tiredness.


    Sore throat, fever, numbness or tingling in hands or feet, cloudy urine, sensitivity to sunlight, jaundice.

Warnings & Precautions

Don't take if:

  • You are allergic to any antifungal medicine.
  • You are allergic to penicillin.
  • You have liver disease.
  • You have porphyria.
  • The infection is minor and will respond to less potent drugs.

Before you start, consult your doctor:

  • If you plan to become pregnant within medication period.
  • If you have liver disease.
  • If you have lupus.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons.

Risk to unborn child outweighs drug benefits. Don't use.

No problems expected, but consult your doctor.

Infants & children:
Not recommended for children younger than 2.

Prolonged use:

  • You may become susceptible to infections caused by germs not responsive to griseofulvin.
  • Talk to your doctor about the need for follow-up medical examinations or laboratory studies to check complete blood counts (white blood cell count, platelet count, red blood cell count, hemoglobin, hematocrit), liver function, kidney function.

Skin & sunlight:
May cause rash or intensify sunburn in areas exposed to sun or sunlamp.

Driving, piloting or hazardous work:

  • Don't drive if you feel dizzy or have vision problems.
  • Don't pilot aircraft.

Don't discontinue without doctor's advice until you complete prescribed dose, even though symptoms diminish or disappear.

Periodic laboratory blood studies and liver- and kidney-function tests recommended.

Possible Interaction with Other Drugs

------------------------ -----------------------
Anticoagulants, Decreased anti-
oral* anticoagulant effect.
Barbiturates* Decreased griseofulvin effect.
Contraceptives, Decreased contraceptive
oral* effect.
Drugs that increase Increased sun hazard.

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: Increased intoxication. Possible
disulfiram reaction*.
Beverages: None expected.
Cocaine: None expected.
Foods: None expected, but foods high in
fat will improve drug absorption.
Marijuana: None expected.
Tobacco: None expected.

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