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Brand & Generic Names


Basic Information

  • Habit forming? No
  • Prescription needed? Yes
  • Available as generic? No
  • Drug class: Antiarrhythmic


    Stabilizes irregular heartbeat.

Dosage & Usage Information

How to take:
Tablet--Swallow with liquid. If you can't swallow whole, crumble tablet and take with liquid or food.

When to take:
At the same time each day, according to instructions on prescription label. Take tablets approximately 12 hours apart.

If you forget a dose:
Take as soon as you remember up to 4 hours late. If more than 4 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Decreases conduction of abnormal electrical activity in the heart muscle or its regulating systems.

Time lapse before drug works:
1 to 6 hours. May need doses daily for 2 to 3 days for maximum effect.

Don't take with:
Any other medicine without consulting your doctor or pharmacist.


Low blood pressure or unconsciousness, irregular or rapid heartbeat, sleepiness, tremor, sweating.


  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • If patient is unconscious and not breathing, give mouth-to- mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). Don't try to make patient vomit. If you can't get help quickly, take patient to nearest emergency facility.
  • See EMERGENCY Information.

Possible Adverse Reactions or Side Effects


    In case of overdose, see Overdose section.


    Blurred vision, dizziness.


  • Chest pain, irregular heartbeat.
  • Shakiness, rash, nausea, vomiting.
  • Anxiety; depression; weakness; headache; appetite loss; weakness in muscles, bones, joints; swollen feet, ankles or legs; loss of taste; numbness or tingling in hands or feet, abdominal pain.
  • Constipation.


  • Shortness of breath.
  • Sore throat, jaundice, fever.

Warnings & Precautions

Don't take if:
You are allergic to flecainide or a local anesthetic such as novocaine, xylocaine or other drug whose generic name ends with "caine."

Before you start, consult your doctor:

  • If you have kidney disease.
  • If you have liver disease.
  • If you have had a heart attack in the past 3 weeks.
  • If you have a pacemaker.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons.

Studies inconclusive on harm to unborn child. Animal studies show fetal abnormalities. Decide with your doctor whether drug benefits justify risk to unborn child.

No proven problems. Consult doctor.

Infants & children:
Not recommended. Safety and dosage have not been established.

Prolonged use:
Talk to your doctor about the need for follow-up medical examinations or laboratory studies to check complete blood counts (white blood cell count, platelet count, red blood cell count, hemoglobin, hematocrit), ECG*.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes, such as antihistamines, tranquilizers, sedatives, pain medicine, narcotics and mind-altering drugs.

Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment.

Wear identification bracelet or carry an identification card with inscription of medicine you take.

Possible Interaction with Other Drugs

------------------------ -----------------------
Antacids* Possible increased
(high dose) flecainide acetate effect.
Antiarrhythmics, Possible irregular
other* heartbeat.
Beta-adrenergic Possible decreased
blockers* efficiency of heart-muscle
contraction, leading to congestive
heart failure.
Bone marrow Possible decreased
depressants* production of blood cells in bone
Carbonic anhydrase Possible increased
inhibitors* flecainide acetate effect.
Cimetidine Increased effect of cimetidine.
Digitalis Possible increased
preparations* digitalis effect. Possible
irregular heartbeat.
Disopyramide Possible decreased efficiency of
heart muscle contraction, leading
to congestive heart failure.
Encainide Increased effect of toxicity on the
heart muscle.
Nicardipine Possible increased effect and
toxicity of each drug.
Paroxetine Increased effect of both drugs.
Propafenone Increased effect of both drugs and
increased risk of toxicity.
Sodium bicarbonate Possible increased flecainide
acetate effect.
Verapamil Possible decreased efficiency of
heart-muscle contraction, leading
to congestive heart failure.

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: May further depress normal heart
Caffeine-containing Possible decreased
beverages. flecainide effect.
Cocaine: Possible decreased flecainide
Foods: None expected.
Marijuana: Possible decreased flecainide
Tobacco: Possible decreased flecainide

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