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Brand & Generic Names

Broncholate Quelidrine Cough
Bronkotuss Expectorant Rentamine Pediatric
Histatuss Pediatric Rynatuss
KIE Rynatuss Pediatric

Basic Information

  • Habit forming? No
  • Prescription needed? Low Strength: No High Strength: Yes
  • Available as generic? Yes, for some.
  • Drug class: Sympathomimetic


  • Relieves bronchial asthma.
  • Decreases congestion of breathing passages.
  • Suppresses allergic reactions.

Dosage & Usage Information

How to take:
Tablet or capsule--Swallow with liquid. You may chew or crush tablet.
Extended-release tablets or capsules--Swallow each dose whole.
Syrup--Take as directed on bottle.
Drops--Dilute dose in beverage.

When to take:
As needed, no more often than every 4 hours.

If you forget a dose:
Take up to 2 hours late. If more than 2 hours, wait for next dose (don't double this dose).

What drug does:
Prevents cells from releasing allergy-causing chemicals (histamines).
Relaxes muscles of bronchial tubes.
Decreases blood vessel size and blood flow, thus causing decongestion.

Time lapse before drug works:
30 to 60 minutes.

Don't take with:
Non-prescription drugs with ephedrine, pseudoephedrine or epinephrine.
Non-prescription drugs for cough, cold, allergy or asthma without consulting doctor.
Any other medicine without consulting your doctor or pharmacist.


Severe anxiety, confusion, delirium, muscle tremors, rapid and irregular pulse.


  • Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
  • See EMERGENCY Information.

Possible Adverse Reactions or Side Effects


    In case of overdose, see Overdose section.


  • Nervousness, headache, paleness, rapid heartbeat.
  • Insomnia.


  • Irregular heartbeat.
  • Dizziness, appetite loss, nausea, vomiting, painful or difficult urination.


    None expected.

Warnings & Precautions

Don't take if:
You are allergic to ephedrine or any sympathomimetic* drug.

Before you start, consult your doctor:

  • If you have high blood pressure.
  • If you have diabetes.
  • If you have overactive thyroid gland.
  • If you have difficulty urinating.
  • If you have taken any MAO inhibitor in past 2 weeks.
  • If you have taken digitalis preparations in the last 7 days.
  • If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.

Over age 60:
More likely to develop high blood pressure, heart-rhythm disturbances, angina and to feel drug's stimulant effects.

Studies inconclusive on harm to unborn child. Decide with you doctor whether drug benefits justify risk to unborn child.

Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine. Consult doctor for advice on maintaining milk supply.

Infants & children:
No problems expected.

Prolonged use:

  • Excessive doses--Rare toxic psychosis.
  • Men with enlarged prostate gland may have more urination difficulty.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
Avoid if you feel dizzy. Otherwise, no problems expected.

May be unnecessary to finish medicine. Follow doctor's instructions.

No problems expected.

Possible Interaction with Other Drugs

------------------------ -----------------------
Antidepressants, Increased effect of
tricyclic (TCA)* ephedrine. Excessive stimulation of
heart and blood pressure.
Antihypertensives* Decreased antihypertensive effect.
Beta-adrenergic Decreased effects
blockers* of both drugs.
Dextrothyroxine Increased ephedrine effect.
Digitalis Serious heart-rhythm
preparations* disturbances.
Epinephrine Increased epinephrine effect.
Ergot Serious blood-
preparations* pressure rise.
Furazolidine Sudden, severe increase in blood
Guanadrel Decreased effect of both drugs.
Guanethidine Decreased effect of both drugs.
MAO inhibitors* Increased ephedrine effect.
Dangerous blood pressure rise.
Methyldopa Possible increased blood pressure.
Nitrates* Possible decreased effects of both
Phenothiazines* Possible increased ephedrine
toxicity. Possible decreased
ephedrine effect.
Pseudoephedrine Increased pseudoephedrine effect.
Rauwolfia Decreased rauwolfia effect.
Sympathomimetics* Increased ephedrine effect.
Terazosin Decreases effectiveness of
Theophylline Increased gastrointestinal

Possible Interaction with Other Substances

--------------- ---------------
Alcohol: None expected.
Caffeine drinks. Nervousness or insomnia.
Cocaine: High risk of heartbeat
irregularities and high blood
Foods: None expected.
Marijuana: Rapid heartbeat, possible heart-
rhythm disturbance.
Tobacco: None expected.

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