Brand & Generic Names
- Habit forming? No
- Prescription needed? Yes
- Available as generic? Yes
- Drug class: None
Treatment for alcoholism. Will not cure alcoholism, but is a
powerful deterrent to drinking.
Dosage & Usage Information
How to take:
Tablet--Swallow with liquid.
When to take:
Morning or bedtime. Avoid if you have used any alcohol, tonics,
cough syrups, fermented vinegar, after-shave lotion or backrub
solutions within 12 hours.
If you forget a dose:
Take as soon as you remember up to 12
hours late. If more than 12 hours, wait for next scheduled dose
(don't double this dose).
What drug does:
In combination with alcohol, produces a metabolic change that
causes severe, temporary toxicity.
Time lapse before drug works:
3 to 12 hours.
Don't take with:
Any other medicine without consulting your doctor or pharmacist.
Non-prescription drugs that contain any alcohol.
Any other central nervous system (CNS) depressant drugs*.
Memory loss, behavior disturbances, lethargy,
confusion and headaches; nausea, vomiting, stomach pain and
diarrhea; weakness and unsteady walk; temporary paralysis.
WHAT TO DO:
- Dial 911 (emergency) or O (operator) for an ambulance or
medical help. Then give first aid immediately.
- See EMERGENCY Information.
Possible Adverse Reactions or Side Effects
In case of overdose, see Overdose section.
- Eye pain, vision
headache, numbness in
hands and feet.
- Mood change,
ability in men,
- Bad taste in mouth
(metal or garlic).
Warnings & Precautions
Don't take if:
- You are allergic to disulfiram (alcohol-disulfiram combination
is not an allergic reaction).
- You have used alcohol in any form or amount within 12 hours.
- You have taken paraldehyde within 1 week.
- You have heart disease.
Before you start, consult your doctor:
- If you have allergies.
- If you plan to become pregnant within medication period.
- If no one has explained to you how disulfiram reacts.
- If you think you cannot avoid drinking.
- If you have diabetes, epilepsy, liver or kidney disease.
- If you take other drugs.
Over age 60:
Adverse reactions and side effects may be more frequent and
severe than in younger persons.
Risk to unborn child outweighs drug benefits. Don't use.
Studies inconclusive. Consult your doctor.
Infants & children:
Periodic blood cell counts and liver function tests recommended
if you take this drug a long time.
Skin & sunlight:
No problems expected.
Driving, piloting or hazardous work:
Avoid if you feel drowsy or have vision side effects. Otherwise,
Don't discontinue without consulting doctor. Dose may require
gradual reduction if you have taken drug for a long time. Doses
of other drugs may also require adjustment. Avoid alcohol at
least 14 days following last dose.
Check all liquids that you take or rub on for presence of
Possible Interaction with Other Drugs
||Possible unexplained bleeding.
||Toxic effect on the central nervous
||Dangerous increased effects of
||ethinamate. Avoid combining.
||Increased depressant effects of
||May increase depressant effects of
||Unsteady walk and disturbed
||High alcohol content of leucovorin
||may cause adverse effects.
||Increased sedative effect, perhaps
||to dangerous level. Avoid.
||Greater depression of central
||Increased paraldehyde effect. Avoid
||Increased depressive effects of
Possible Interaction with Other Substances
|Any form or
||See disulfiram reaction*.
|Punch or fruit drink
||Increased disulfiram effect.