CLOTRIMAZOLE (Oral-Local)

Brand & Generic Names

Mycelex

Basic Information

• Habit forming? No
• Prescription needed? Yes
• Available as generic? No
• Drug class: Antifungal

Uses

• Treats thrush, white mouth (candidiasis).
• Used primarily in immunosuppressed patients to treat and prevent mouth infection.

Dosage & Usage Information

How to take:
Lozenges--Dissolve slowly and completely in the mouth, 5 times a day. Swallow saliva during this time. Don't swallow lozenge whole and don't chew.

When to take:
14 days or longer.

If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Kills fungus by interfering with cell wall membrane and its permeability.

Time lapse before drug works:
1 to 3 hours.

Don't take with:
Any other medicine without consulting your doctor or pharmacist.

Overdose

SYMPTOMS:
None expected, but if large dose has been taken, follow instructions below.

WHAT TO DO:

• Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
• See EMERGENCY Information.

Possible Adverse Reactions or Side Effects

Life-threatening:

None expected.

Common:

None expected.

Infrequent:

Abdominal pain, diarrhea, nausea, vomiting.

Rare:

None expected.

Warnings & Precautions

Don't take if:
You have severe liver disease.

Before you start, consult your doctor:
If you have had a recent organ transplant.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons. You may need smaller doses for shorter periods of time.

Pregnancy:
Risk to unborn child outweighs drug benefits. Don't use.

Breast-feeding:
Unknown effect. Consult doctor.

Infants & children:
Use only under medical supervision for children younger than 4 or 5 years.

Prolonged use:
No problems expected.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes.

Discontinuing:
Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment.

Others:

• Continue for full term of treatment. May require several months.
• Check with physician if not improved in 1 week.

Possible Interaction with Other Drugs

GENERIC NAME	COMBINED EFFECT
------------------------	-----------------------

Possible Interaction with Other Substances

INTERACTS WITH	COMBINED EFFECT
---------------	---------------
Alcohol:	Decreased effects of clotrimazole.
Beverages:	None expected.
Cocaine:	Decreased effects of clotrimazole.
Foods:	None expected.
Marijuana:	Decreased effects of clotrimazole.
Tobacco:	Decreased effects of clotrimazole.