CLOMIPHENE

Brand & Generic Names

Clomid
Milophene
Serophene

Basic Information

• Habit forming? No
• Prescription needed? Yes
• Available as generic? Yes
• Drug class: Gonad stimulant

Uses

• Treatment for men with low sperm counts.
• Treatment for ovulatory failure in women who wish to become pregnant.

Dosage & Usage Information

How to take:
Tablet--Swallow with liquid.

When to take:
Men--Take at the same time each day.
Women--Follow physician's instructions carefully.

If you forget a dose:
Take as soon as you remember. If you forget a day, double next dose. If you miss 2 or more doses, consult doctor.

What drug does:
Antiestrogen effect stimulates ovulation and sperm production.

Time lapse before drug works:
Usually 3 to 6 months. Ovulation may occur 6 to 10 days after last day of treatment in any cycle.

Don't take with:
No restrictions.

Overdose

SYMPTOMS:
Increased severity of adverse reactions and side effects.

WHAT TO DO:

Overdose unlikely to threaten life. If person takes much larger amount than prescribed, call doctor, poison-control center or hospital emergency room for instructions.

Possible Adverse Reactions or Side Effects

Life-threatening:

Sudden shortness of breath. Seek emergency treatment.

Common:

• Bloating, abdominal pain, pelvic pain.
• Hot flashes.

Infrequent:

• Rash, itch, vomiting, jaundice.
• Constipation, diarrhea, increased appetite, heavy menstrual flow, frequent urination, breast discomfort, weight change, hair loss, nausea.

Rare:

• Vision changes.
• Dizziness, headache, tiredness, depression, nervousness.

Warnings & Precautions

Don't take if:
You are allergic to clomiphene.

Before you start, consult your doctor:

• If you have an ovarian cyst, fibroid uterine tumors or unusual vaginal bleeding.
• If you have inflamed veins caused by blood clots.
• If you have liver disease.
• If you are depressed.

Over age 60:
Not recommended.

Pregnancy:
Stop taking at first sign of pregnancy.

Breast-feeding:
Not used.

Infants & children:
Not used.

Prolonged use:

• Not recommended.
• Talk to your doctor about the need for follow-up medical examinations or laboratory studies to check basal body temperature, endometrial biopsy, kidney function, eyes.

Skin & sunlight:
Eyes more sensitive to light.

Driving, piloting or hazardous work:

• Avoid if you feel dizzy.
• May cause blurred vision.

Discontinuing:
May be unnecessary to finish medicine. Follow doctor's instructions.

Others:

• Have a complete pelvic examination before treatment.
• If you become pregnant, twins or triplets are possible.

Possible Interaction with Other Drugs

GENERIC NAME	COMBINED EFFECT
------------------------	-----------------------
Thyroglobulin	May increase serum thyroglobulin.
Thyroxine (T-4)	May increase serum thyroxine.

Possible Interaction with Other Substances

INTERACTS WITH	COMBINED EFFECT
---------------	---------------
Alcohol:	None expected.
Beverages:	None expected.
Cocaine:	None expected.
Foods:	None expected.
Marijuana:	None expected.
Tobacco:	None expected.