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May 18, 2013 (time zone GMT 00:00) Sources quantity: 179 Articles quantity: 817702

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  HOME > Cholesterol > Cholesterol’s other way out
 

Cholesterol’s other way out




Many of us are simply overloaded with cholesterol, and now a report in the July issue of Cell Metabolism brings what might be good news: There is more than one way to get rid of that cholesterol, which can otherwise lead to atherosclerosis and heart disease. “Cholesterol really can’t be broken down,” said Mark Brown of Wake Forest University School of Medicine. To get rid of it, it must be excreted, and now Brown and his colleagues have new evidence for an alternate way to deliver cholesterol into the feces. The findings revise scientific dogma about cholesterol loss that goes back almost 40 years. Textbooks say that white blood cells known as macrophages gobble up cholesterol from artery walls. That cholesterol is then delivered to high-density lipoprotein [HDL, aka good cholesterol], which takes it back to the liver where it goes into bile. 




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